Reactome | OPRD1 [plasma membrane]

OPRD1 [plasma membrane]

Stable Identifier

R-CFA-374265

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

OPRD1, A0A8I3NAD1

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (i) signalling events (Canis familiaris)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Opioid receptor:opioid ligand [plasma membrane] (Canis familiaris)
        
        Opioid receptors [plasma membrane] (Canis familiaris)
        
        OPRD1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Opioid receptor:opioid ligand [plasma membrane] (Canis familiaris)
        
        Opioid receptors [plasma membrane] (Canis familiaris)
        
        OPRD1 [plasma membrane] (Canis familiaris)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Opioid receptor:opioid ligand [plasma membrane] (Canis familiaris)
        
        Opioid receptors [plasma membrane] (Canis familiaris)
        
        OPRD1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Opioid receptor:opioid ligand [plasma membrane] (Canis familiaris)
        
        Opioid receptors [plasma membrane] (Canis familiaris)
        
        OPRD1 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Opioid receptor:opioid ligand [plasma membrane] (Canis familiaris)
        
        Opioid receptors [plasma membrane] (Canis familiaris)
        
        OPRD1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Opioid receptor:opioid ligand [plasma membrane] (Canis familiaris)
        
        Opioid receptors [plasma membrane] (Canis familiaris)
        
        OPRD1 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Peptide ligand-binding receptors (Canis familiaris)
        
        Opioid receptors bind opioid peptides (Canis familiaris)
        
        Opioid receptor:opioid ligand [plasma membrane] (Canis familiaris)
        
        Opioid receptors [plasma membrane] (Canis familiaris)
        
        OPRD1 [plasma membrane] (Canis familiaris)
        
        Opioid receptors [plasma membrane] (Canis familiaris)
        
        OPRD1 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NAD1

Gene Names

OPRD1

Reference Genes

ENSEMBL:ENSCAFG00845009543.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845009543.1 OPRD1

Other Identifiers

487329

CfaAffx.18163.1.S1_at

GO:0004930

GO:0004985

GO:0005886

GO:0007165

GO:0007186

GO:0007193

GO:0007218

GO:0008344

GO:0010629

GO:0016020

GO:0023052

GO:0031333

GO:0031410

GO:0033138

GO:0036211

GO:0038003

GO:0038046

GO:0043226

GO:0051881

GO:0060089

GO:0065003

GO:0071456

GO:0097237

GO:0098992

Participates

as a member of

Opioid receptors [plasma membrane] (Canis familiaris)

Inferred From

OPRD1 [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000116329

Ensembl

ENSCAFT00845016801, ENSCAFG00845009543, ENSCAFP00845013064