Reactome | LPAR5 [plasma membrane]

LPAR5 [plasma membrane]

Stable Identifier

R-CFA-3249414

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

LPAR5, A0A8I3SBJ6

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (i) signalling events (Canis familiaris)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5 [plasma membrane] (Canis familiaris)
        
        LPAR5 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5 [plasma membrane] (Canis familiaris)
        
        LPAR5 [plasma membrane] (Canis familiaris)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5 [plasma membrane] (Canis familiaris)
        
        LPAR5 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5 [plasma membrane] (Canis familiaris)
        
        LPAR5 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5 [plasma membrane] (Canis familiaris)
        
        LPAR5 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5 [plasma membrane] (Canis familiaris)
        
        LPAR5 [plasma membrane] (Canis familiaris)
    - G alpha (q) signalling events (Canis familiaris)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5 [plasma membrane] (Canis familiaris)
        
        LPAR5 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5 [plasma membrane] (Canis familiaris)
        
        LPAR5 [plasma membrane] (Canis familiaris)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5 [plasma membrane] (Canis familiaris)
        
        LPAR5 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5 [plasma membrane] (Canis familiaris)
        
        LPAR5 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
        
        GPCRs that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5 [plasma membrane] (Canis familiaris)
        
        LPAR5 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5 [plasma membrane] (Canis familiaris)
        
        LPAR5 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Lysosphingolipid and LPA receptors (Canis familiaris)
        
        LPA-binding receptors bind LPA (Canis familiaris)
        
        LPAR1,2,3,5 [plasma membrane] (Canis familiaris)
        
        LPAR5 [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
        
        LPAR1,2,3,5 [plasma membrane] (Canis familiaris)
        
        LPAR5 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3SBJ6

Gene Names

LPAR5

Reference Genes

BioGPS Gene:486724 LPAR5

ENSEMBL:ENSCAFG00845028579.1

KEGG:cfa:486724 LPAR5

Monarch:486724 LPAR5

NCBI Gene:486724 LPAR5

UCSC:A0A8I3SBJ6 LPAR5

Reference Transcript

Other Identifiers

486724

CfaAffx.22770.1.S1_at

GO:0004930

GO:0005886

GO:0007186

GO:0016020

GO:0048266

GO:0060089

Participates

as a member of

LPAR1,2,3,5 [plasma membrane] (Canis familiaris)

Inferred From

LPAR5 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_038295128.1, XP_038295127.1, XP_038295129.1, XP_005637298.1, XP_013963960.1, XP_005637300.1, XP_038295131.1, XP_005637295.1, XP_005637296.1, XP_038315675.1, XP_038315674.1, XP_013963958.1, XP_013963959.1, XP_038295130.1

ENSEMBL

ENSCAFT00845050461, ENSCAFT00845050446, ENSCAFP00845039537, ENSCAFT00845050469, ENSCAFG00845028579, ENSCAFT00845050428, ENSCAFP00845039565, ENSCAFP00845039572, ENSCAFP00845039552