Reactome | LMNA [nucleoplasm]

LMNA [nucleoplasm]

Stable Identifier

R-CFA-264866

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

Lamin A, J9NSW5

Locations in the PathwayBrowser

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Cell Cycle (Canis familiaris)

- Cell Cycle, Mitotic (Canis familiaris)
  - M Phase (Canis familiaris)
    - Mitotic Metaphase and Anaphase (Canis familiaris)
      - Mitotic Anaphase (Canis familiaris)
        
        Nuclear Envelope (NE) Reassembly (Canis familiaris)
        
        Initiation of Nuclear Envelope (NE) Reformation (Canis familiaris)
        
        BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Canis familiaris)
        
        EMD/TMPO/LEMD3/LEMD2:Lamin filaments:BANF1:Chromatin [nuclear envelope] (Canis familiaris)
        
        Lamin filaments [nucleoplasm] (Canis familiaris)
        
        Lamin dimers [nucleoplasm] (Canis familiaris)
        
        Lamin A dimer [nucleoplasm] (Canis familiaris)
        
        LMNA [nucleoplasm] (Canis familiaris)
    - Mitotic Prophase (Canis familiaris)
      - Nuclear Envelope Breakdown (Canis familiaris)
        
        Depolymerisation of the Nuclear Lamina (Canis familiaris)
        
        Depolymerization of lamin filaments after PKC-mediated phosphorylation (Canis familiaris)
        
        EMD/TMPO/LEMD3/LEMD2:Lamin filaments [nuclear envelope] (Canis familiaris)
        
        Lamin filaments [nucleoplasm] (Canis familiaris)
        
        Lamin dimers [nucleoplasm] (Canis familiaris)
        
        Lamin A dimer [nucleoplasm] (Canis familiaris)
        
        LMNA [nucleoplasm] (Canis familiaris)
        
        VRK1/VRK2 phosphorylate BANF1 (Canis familiaris)
        
        EMD/TMPO/LEMD3/LEMD2:Lamin filaments [nuclear envelope] (Canis familiaris)
        
        Lamin filaments [nucleoplasm] (Canis familiaris)
        
        Lamin dimers [nucleoplasm] (Canis familiaris)
        
        Lamin A dimer [nucleoplasm] (Canis familiaris)
        
        LMNA [nucleoplasm] (Canis familiaris)
        
        EMD/TMPO/LEMD3/LEMD2:Lamin filaments:BANF1:Chromatin [nuclear envelope] (Canis familiaris)
        
        Lamin filaments [nucleoplasm] (Canis familiaris)
        
        Lamin dimers [nucleoplasm] (Canis familiaris)
        
        Lamin A dimer [nucleoplasm] (Canis familiaris)
        
        LMNA [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:J9NSW5

Gene Names

LMNA

Reference Genes

ENSEMBL:ENSCAFG00000016863

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000016863 LMNA

Other Identifiers

480124

Cfa.3304.3.S1_s_at

GO:0005575

GO:0005622

GO:0005856

GO:0005882

GO:0043226

Participant Of

input

Caspase-mediated cleavage of Lamin A

hasComponent

Lamin A dimer [nucleoplasm]

Other forms of this molecule

LMNA [nuclear envelope]

phospho-LMNA [nucleoplasm]

LMNA [nucleoplasm]

LMNA [cytosol]

Inferred From

Lamin A [nucleoplasm] (Homo sapiens)

Cross References

Target Pathogen

5b354852be737e166372e748

OpenTargets

ENSG00000160789

Ensembl

ENSCAFG00000016863, ENSCAFP00000041817, ENSCAFT00000045788

VGNC

42717