Reactome | PDS5A [chromosome, centromeric region]

PDS5A [chromosome, centromeric region]

Stable Identifier

R-CFA-2468259

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

chromosome, centromeric region

Synonyms

PDS5A, A0A8I3MTB9

Locations in the PathwayBrowser

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Cell Cycle (Canis familiaris)

- Cell Cycle, Mitotic (Canis familiaris)
  - M Phase (Canis familiaris)
    - Mitotic Metaphase and Anaphase (Canis familiaris)
      - Mitotic Anaphase (Canis familiaris)
        
        Separation of Sister Chromatids (Canis familiaris)
        
        ESPL1 (Separase) cleaves centromeric cohesin (Canis familiaris)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
        
        PDS5 [chromosome, centromeric region] (Canis familiaris)
        
        PDS5A [chromosome, centromeric region] (Canis familiaris)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
        
        PDS5 [chromosome, centromeric region] (Canis familiaris)
        
        PDS5A [chromosome, centromeric region] (Canis familiaris)
        
        Separation of sister chromatids (Canis familiaris)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
        
        PDS5 [chromosome, centromeric region] (Canis familiaris)
        
        PDS5A [chromosome, centromeric region] (Canis familiaris)
    - Mitotic Prometaphase (Canis familiaris)
      - Resolution of Sister Chromatid Cohesion (Canis familiaris)
        
        CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Canis familiaris)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Canis familiaris)
        
        PDS5 [chromosome, centromeric region] (Canis familiaris)
        
        PDS5A [chromosome, centromeric region] (Canis familiaris)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
        
        PDS5 [chromosome, centromeric region] (Canis familiaris)
        
        PDS5A [chromosome, centromeric region] (Canis familiaris)
        
        Kinetochore assembly (Canis familiaris)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Canis familiaris)
        
        PDS5 [chromosome, centromeric region] (Canis familiaris)
        
        PDS5A [chromosome, centromeric region] (Canis familiaris)
        
        Sister Centromeres:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Canis familiaris)
        
        Centromere:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Canis familiaris)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Canis familiaris)
        
        PDS5 [chromosome, centromeric region] (Canis familiaris)
        
        PDS5A [chromosome, centromeric region] (Canis familiaris)
        
        PP2A-B56 dephosphorylates centromeric cohesin (Canis familiaris)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
        
        PDS5 [chromosome, centromeric region] (Canis familiaris)
        
        PDS5A [chromosome, centromeric region] (Canis familiaris)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
        
        PDS5 [chromosome, centromeric region] (Canis familiaris)
        
        PDS5A [chromosome, centromeric region] (Canis familiaris)
        
        Phosphorylation of cohesin by PLK1 at centromeres (Canis familiaris)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
        
        PDS5 [chromosome, centromeric region] (Canis familiaris)
        
        PDS5A [chromosome, centromeric region] (Canis familiaris)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
        
        PDS5 [chromosome, centromeric region] (Canis familiaris)
        
        PDS5A [chromosome, centromeric region] (Canis familiaris)
  - S Phase (Canis familiaris)
    - Establishment of Sister Chromatid Cohesion (Canis familiaris)
      - CDCA5 (Sororin) enables cohesion of sister centromeres (Canis familiaris)
        
        Sister Centromeres:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Canis familiaris)
        
        Centromere:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Canis familiaris)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Canis familiaris)
        
        PDS5 [chromosome, centromeric region] (Canis familiaris)
        
        PDS5A [chromosome, centromeric region] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3MTB9

Gene Names

PDS5A

Reference Genes

ENSEMBL:ENSCAFG00845004259.1

UCSC:A0A8I3MTB9 PDS5A

Reference Transcript

RefSeq:XM_014112318.1 PDS5A

Other Identifiers

479103

Cfa.5812.1.S1_s_at

Cfa.9936.1.A1_at

CfaAffx.24443.1.S1_s_at

CfaAffx.24451.1.S1_at

GO:0000785

GO:0005634

GO:0005654

GO:0005886

GO:0006281

GO:0007064

GO:0008156

GO:0043226

Participates

as a member of

PDS5 [chromosome, centromeric region] (Canis familiaris)

Other forms of this molecule

PDS5A [cytosol]

PDS5A [chromosome]

PDS5A [nucleoplasm]

Inferred From

PDS5A [chromosome, centromeric region] (Homo sapiens)

Cross References

RefSeq

XP_013967793.1

ENSEMBL

ENSCAFG00845004259, ENSCAFT00845007724, ENSCAFP00845006114

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