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About
What is Reactome ?
News
Team
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Our Logo
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Privacy Notice
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Digital Preservation
Contact us
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Table of Contents
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COVID-19 Disease Pathways
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JAK2 [cytosol]
Stable Identifier
R-CFA-210620
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
A0A8I3NVH4
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Growth hormone receptor signaling (Canis familiaris)
JAK2 phosphorylation (Canis familiaris)
PRLR ligands:Activated PRLR:JAK2 dimer:SH2B1 beta [plasma membrane] (Canis familiaris)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Lyn activates ERK (Canis familiaris)
Growth Hormone:Growth Hormone Receptor-JAK2 dimer:LYN [plasma membrane] (Canis familiaris)
Growth Hormone: Growth Hormone Receptor-JAK2 dimer [plasma membrane] (Canis familiaris)
Growth Hormone Receptor-JAK2 dimer [plasma membrane] (Canis familiaris)
Growth Hormone Receptor:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interferon Signaling (Canis familiaris)
Interferon gamma signaling (Canis familiaris)
IFNG dimer binds IFNGR (Canis familiaris)
IFNG:IFNGR1:JAK1:IFNGR2:JAK2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] (Canis familiaris)
IFNGR2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] (Canis familiaris)
IFNGR2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] (Canis familiaris)
IFNGR2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] (Canis familiaris)
IFNGR2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Phosphorylation of JAK2 (Canis familiaris)
IFNG:IFNGR1:JAK1:IFNGR2:JAK2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] (Canis familiaris)
IFNGR2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Prolactin receptor signaling (Canis familiaris)
JAK2 phosphorylation (Canis familiaris)
PRLR ligands:Activated PRLR:JAK2 dimer:SH2B1 beta [plasma membrane] (Canis familiaris)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
PRLR activation (Canis familiaris)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
PRLR binds SCF beta-TrCP complex (Canis familiaris)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Canis familiaris)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
p(S349)-PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
p(S349)-PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
p(S349)-PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
p(S349)-PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
PRLR is phosphorylated at Ser-349 (Canis familiaris)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
p(S349)-PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
p(S349)-PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
PRLR:JAK2 dimerizes (Canis familiaris)
PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Prolactin receptor is internalized (Canis familiaris)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Canis familiaris)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
p(S349)-PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
p(S349)-PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Prolactin receptor ligands bind the prolactin receptor (Canis familiaris)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Canis familiaris)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
p(S349)-PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
p(S349)-PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
SH2B binds JAK2 (Canis familiaris)
PRLR ligands:Activated PRLR:JAK2 dimer:SH2B1 beta [plasma membrane] (Canis familiaris)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 dimer [plasma membrane] (Canis familiaris)
PRLR:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-12 family signaling (Canis familiaris)
Interleukin-12 signaling (Canis familiaris)
IL12 bound to IL12R internalises (Canis familiaris)
IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB1:TYK2:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL12RB1:TYK2 binds IL12RB2:JAK2 (Canis familiaris)
IL12RB1:TYK2:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin-12 binds Interleukin-12 receptor (Canis familiaris)
IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB1:TYK2:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL12RB1:TYK2:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin-12 dissociates from Interleukin-12 receptor (Canis familiaris)
IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB1:TYK2:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL12RB1:TYK2:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Canis familiaris)
IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB1:TYK2:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin-23 signaling (Canis familiaris)
Interleukin-23 binds interleukin-23 receptor (Canis familiaris)
IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 [plasma membrane] (Canis familiaris)
IL23R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL23R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin-27 signaling (Canis familiaris)
Interleukin-27 binds Interleukin-27 receptor (Canis familiaris)
IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin-27 dissociates from Interleukin-27 receptor (Canis familiaris)
IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Canis familiaris)
IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin-35 Signalling (Canis familiaris)
IL35 binds IL-12RB2:IL6ST receptor (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL35 binds IL12RB2:IL12RB2 receptor (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL35:(IL12RB2:JAK2 dimer) [plasma membrane] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL35 binds IL27RA:IL12RB2 receptor (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL35:IL27RA:JAK1:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL35 binds IL6ST:IL6ST receptor (Canis familiaris)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Canis familiaris)
IL35:IL27RA:JAK1:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Canis familiaris)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Canis familiaris)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Canis familiaris)
IL35:(IL12RB2:JAK2 dimer) [plasma membrane] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin-2 family signaling (Canis familiaris)
Interleukin receptor SHC signaling (Canis familiaris)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Phosphorylated SHC recruits GRB2:SOS1 (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Phosphorylated SHC1 recruits GRB2:GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Phosphorylated SHC1 recruits SHIP (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
The SHC1:SHIP1 complex is stabilized by GRB2 (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin-20 family signaling (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB binds JAK2,JAK3 (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 [plasma membrane] (Canis familiaris)
JAK2, JAK3 [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK2, JAK3 [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 [plasma membrane] (Canis familiaris)
JAK2, JAK3 [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Canis familiaris)
14-3-3 zeta binding allows recruitment of PI3K (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(S585)-Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(S585)-Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
IL3:IL3RA:pS585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(S585)-Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(S585)-Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
IL3:IL3RA:pS585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
GM-CSF receptor alpha:GM-CSF binds Bc (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3RB is phosphorylated on Ser-585 (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(S585)-Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(S585)-Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
IL3:IL3RA:pS585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin receptor SHC signaling (Canis familiaris)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Phosphorylated SHC recruits GRB2:SOS1 (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Phosphorylated SHC1 recruits GRB2:GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Phosphorylated SHC1 recruits SHIP (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
The SHC1:SHIP1 complex is stabilized by GRB2 (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin-5:Interleukin-5 receptor alpha binds IL3RB:JAK2 (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK2 is phosphorylated, activated (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Recruitment of SHC1 is mediated by Y593 of the common beta chain (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
SHP1 and SHP2 bind the common beta chain (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593)-Bc:SHP1, SHP2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593)-Bc [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593)-Bc:JAK2 [plasma membrane] (Canis familiaris)
p(Y593)-Bc:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593)-Bc:JAK2 [plasma membrane] (Canis familiaris)
p(Y593)-Bc:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, p(Y593)-Bc [plasma membrane] (Canis familiaris)
IL3RA:IL3:p(Y593)-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
p(Y593)-Bc:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
The receptor is activated (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity binding complexes of interleukin receptors using the Common beta chain [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Tyrosine kinases phosphorylate the receptor (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Tyrosine kinases that phosphorylate the Common beta chain [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
p-S585-IL3RB binds 14-3-3 proteins (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(S585)-Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(S585)-Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
IL3:IL3RA:pS585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(S585)-Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(S585)-Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Canis familiaris)
IL3:IL3RA:pS585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin-4 and Interleukin-13 signaling (Canis familiaris)
IL13:IL13RA:TYK2 binds IL4R:JAK2 (Canis familiaris)
IL13:IL13RA:TYK2:IL4R:JAK2 [plasma membrane] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL4 binds IL4R:JAK2 (Canis familiaris)
IL4:IL4R:JAK2 [plasma membrane] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL4:IL4R:JAK2 binds IL13RA1:TYK2 (Canis familiaris)
IL4:IL4R:JAK2 [plasma membrane] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL4:IL4R:JAK2:IL13RA1:TYK2 [plasma membrane] (Canis familiaris)
IL4:IL4R:JAK2 [plasma membrane] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL4R binds JAK2 (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Canis familiaris)
IL13:IL13RA:TYK2:IL4R:JAK2:JAK1 [plasma membrane] (Canis familiaris)
IL13:IL13RA:TYK2:IL4R:JAK2 [plasma membrane] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Canis familiaris)
IL4:IL4R:JAK2:IL2RG:JAK3:JAK1 [plasma membrane] (Canis familiaris)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL4:IL4R:JAK2 [plasma membrane] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK1 binds IL4R in IL13-bound IL13R type II (Canis familiaris)
IL13:IL13RA:TYK2:IL4R:JAK2 [plasma membrane] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL13:IL13RA:TYK2:IL4R:JAK2:JAK1 [plasma membrane] (Canis familiaris)
IL13:IL13RA:TYK2:IL4R:JAK2 [plasma membrane] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK1 binds IL4R in IL4-bound IL4R1 (Canis familiaris)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL4:IL4R:JAK2 [plasma membrane] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL4:IL4R:JAK2:IL2RG:JAK3:JAK1 [plasma membrane] (Canis familiaris)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL4:IL4R:JAK2 [plasma membrane] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK1 phosphorylates STAT3,STAT6 (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1:STAT3,STAT6 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1:p-Y705-STAT3,p-Y641-STAT6 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
SOCS5,(SOCS1) bind IL4RA (Canis familiaris)
IL4:IL4R:JAK2:IL13RA1:TYK2 [plasma membrane] (Canis familiaris)
IL4:IL4R:JAK2 [plasma membrane] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL4:IL4R:JAK2:IL13RA:TYK2:SOCS5,(SOCS1) [plasma membrane] (Canis familiaris)
IL4:IL4R:JAK2:IL13RA1:TYK2 [plasma membrane] (Canis familiaris)
IL4:IL4R:JAK2 [plasma membrane] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
STAT3,STAT6 bind p-Y-IL4R (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1:STAT3,STAT6 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
p-Y705-STAT3,p-Y641-STAT6 dissociate (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1:p-Y705-STAT3,p-Y641-STAT6 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL4:p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin-6 family signaling (Canis familiaris)
IL-6-type cytokine receptor ligand interactions (Canis familiaris)
CTF1 binds LIFR:JAKs (Canis familiaris)
CTF1:LIFR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Canis familiaris)
IL6RA:IL6:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAKs bind LIFR (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAKs bind OSMR (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAKs:OSMR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
LIF binds LIFR (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
LIF:LIFR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
LIFR:JAKs bind gp130:JAKs:CNTFR (Canis familiaris)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:gp130:JAKs:LIFR:JAKs [plasma membrane] (Canis familiaris)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
OSM binds LIFR:JAKs,OSMR:JAKs (Canis familiaris)
LIFR:JAKs,OSMR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAKs:OSMR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
OSM:OSMR,LIFR [plasma membrane] (Canis familiaris)
LIFR:JAKs,OSMR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAKs:OSMR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
OSM,LIF,CTF1 receptor complex binds gp130 (Canis familiaris)
LIF,OSM receptor complex:gp130 [plasma membrane] (Canis familiaris)
LIF,OSM,CTF1 receptor complex [plasma membrane] (Canis familiaris)
CTF1:LIFR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
LIF:LIFR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
OSM:OSMR,LIFR [plasma membrane] (Canis familiaris)
LIFR:JAKs,OSMR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAKs:OSMR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
LIF,OSM,CTF1 receptor complex [plasma membrane] (Canis familiaris)
CTF1:LIFR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
LIF:LIFR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
OSM:OSMR,LIFR [plasma membrane] (Canis familiaris)
LIFR:JAKs,OSMR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAKs:OSMR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
gp130:JAKs bind CNTFR (Canis familiaris)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Interleukin-6 signaling (Canis familiaris)
Assembly of hexameric IL-6 receptor (Canis familiaris)
IL6 receptor hexamer:JAKs [plasma membrane] (Canis familiaris)
IL6 receptor trimer:JAKs [plasma membrane] (Canis familiaris)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6 receptor trimer:JAKs [plasma membrane] (Canis familiaris)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Canis familiaris)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) (Canis familiaris)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK activation (Canis familiaris)
IL6 receptor hexamer:JAKs [plasma membrane] (Canis familiaris)
IL6 receptor trimer:JAKs [plasma membrane] (Canis familiaris)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
RAF activation (Canis familiaris)
Phosphorylation of RAF (Canis familiaris)
RAF activating kinases [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
RAS GEFs promote RAS nucleotide exchange (Canis familiaris)
RAS GEFs [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] (Canis familiaris)
GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Signaling by Erythropoietin (Canis familiaris)
EPOR binds EPOR agonists (Canis familiaris)
EPOR agonists:EPOR:JAK2:LYN:IRS2 [plasma membrane] (Canis familiaris)
EPOR:JAK2:LYN:IRS2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
EPOR:JAK2:LYN:IRS2 [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by SCF-KIT (Canis familiaris)
JAK2 binds to p-KIT (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK2:SFKS:p-KIT complex [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
Phosphorylation of JAK2 (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
JAK2:SFKS:p-KIT complex [plasma membrane] (Canis familiaris)
JAK2 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3NVH4
Reference Genes
ENSEMBL:ENSCAFG00845015887.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845015887.1
Other Identifiers
484185
Cfa.16973.1.S1_at
CfaAffx.4076.1.S1_s_at
GO:0000166
GO:0001774
GO:0002250
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005102
GO:0005143
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005856
GO:0005886
GO:0005901
GO:0005925
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0006366
GO:0006468
GO:0006954
GO:0007155
GO:0007165
GO:0007167
GO:0007259
GO:0008284
GO:0008285
GO:0010572
GO:0010811
GO:0012501
GO:0012505
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0019221
GO:0019897
GO:0019901
GO:0020037
GO:0023052
GO:0030099
GO:0030154
GO:0030218
GO:0030526
GO:0031234
GO:0032496
GO:0032729
GO:0032731
GO:0032760
GO:0032819
GO:0033209
GO:0034050
GO:0034612
GO:0035166
GO:0035401
GO:0035556
GO:0035722
GO:0036016
GO:0036211
GO:0038043
GO:0038065
GO:0038156
GO:0038157
GO:0042060
GO:0042102
GO:0042169
GO:0042393
GO:0042531
GO:0042802
GO:0043066
GO:0043226
GO:0043687
GO:0045121
GO:0045348
GO:0045944
GO:0046427
GO:0046677
GO:0048856
GO:0050727
GO:0051142
GO:0051770
GO:0051897
GO:0060391
GO:0060396
GO:0060397
GO:0060399
GO:0061180
GO:0070665
GO:0070671
GO:0071222
GO:0071549
GO:0097191
GO:0098542
GO:0120162
GO:0140096
GO:1901731
GO:2001235
Participates
as a component of
IL23R:JAK2 [plasma membrane] (Canis familiaris)
IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
p(Y593)-Bc:JAK2 [plasma membrane] (Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
p(S349)-PRLR:JAK2 [plasma membrane] (Canis familiaris)
Growth Hormone Receptor:JAK2 [plasma membrane] (Canis familiaris)
PRLR:JAK2 [plasma membrane] (Canis familiaris)
EPOR:JAK2:LYN:IRS2 [plasma membrane] (Canis familiaris)
JAK2:SFKS:p-KIT complex [plasma membrane] (Canis familiaris)
IL4R:JAK2 [plasma membrane] (Canis familiaris)
p-Y-IL4R:JAK2 [plasma membrane] (Canis familiaris)
IFNGR2:JAK2 [plasma membrane] (Canis familiaris)
IL3RB:JAK2 [plasma membrane] (Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane] (Canis familiaris)
as a candidate of
JAK2, JAK3 [cytosol] (Canis familiaris)
RAF activating kinases [plasma membrane] (Canis familiaris)
as a member of
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
as an input of
JAK2 binds to p-KIT (Canis familiaris)
IL4R binds JAK2 (Canis familiaris)
Other forms of this molecule
phospho-p-Y1007,Y1008-JAK2 [cytosol]
phospho-p-JAK2 [cytosol]
phospho-p-Y813-JAK2 [cytosol]
JAK2 [endosome lumen]
phospho-p-12Y-JAK2 [cytosol]
phospho-p-Y1007-JAK2 [cytosol]
Inferred From
JAK2 [cytosol]
(Homo sapiens)
Cross References
Ensembl
ENSCAFG00845015887
,
ENSCAFP00845022298
,
ENSCAFT00845028345
© 2024
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