Reactome | GRB7 [cytosol]

GRB7 [cytosol]

Stable Identifier

R-CFA-204819

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

GRB7, A0A8I3NID0

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:A0A8I3NID0

Gene Names

GRB7

Reference Genes

ENSEMBL:ENSCAFG00845011327.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845011327.1 GRB7

Other Identifiers

491021

CfaAffx.25031.1.S1_at

CfaAffx.25032.1.S1_s_at

GO:0005737

GO:0005829

GO:0005925

GO:0007165

GO:0008289

GO:0010494

GO:0017148

GO:0019901

GO:0023052

GO:0030335

GO:0034063

GO:0035091

GO:0042802

GO:0043226

GO:0048870

Participates

as a member of

RND1 effectors [cytosol] (Canis familiaris)
GRB7,GRB10 [cytosol] (Canis familiaris)
Adapter proteins [cytosol] (Canis familiaris)

as an input of

Interaction of Tie2 and Grb7 (Canis familiaris)
GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Canis familiaris)
Grb7 binds to the active PDGF receptor (Canis familiaris)

as a component of

Tie2:Grb7 complex [plasma membrane] (Canis familiaris)
NRG1/2:p-10Y-ERBB3:p-ERBB2:GRB7 [plasma membrane] (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:Grb7 [plasma membrane] (Canis familiaris)

Inferred From

GRB7 [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000141738

Ensembl

ENSCAFG00845011327, ENSCAFP00845015815, ENSCAFT00845020177