Reactome | F1Q184 [plasma membrane]

F1Q184 [plasma membrane]

Stable Identifier

R-CFA-2038821

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Locations in the PathwayBrowser

Expand all

Immune System (Canis familiaris)

- Adaptive Immune System (Canis familiaris)
  - Signaling by the B Cell Receptor (BCR) (Canis familiaris)
    - Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Canis familiaris)
      - BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate (Canis familiaris)
        
        BLNK (SLP-65) Signalosome [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR:p-SYK [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
      - Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 (Canis familiaris)
        
        Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR:p-SYK [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2 [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR:p-SYK [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
      - SYK autophosphorylates at the activated BCR (Canis familiaris)
        
        Antigen:p-BCR:SYK [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR:p-SYK [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        PTPN6:p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
      - SYK binds the activated BCR (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR:SYK [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
      - The Immunoglobulin of the BCR binds antigen (Canis familiaris)
        
        Antigen:BCR [plasma membrane] (Canis familiaris)
        
        BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
      - p-6Y-SYK phosphorylates BLNK (SLP65) (Canis familiaris)
        
        Antigen:p-BCR:p-SYK [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR:p-SYK [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
    - CD22 mediated BCR regulation (Canis familiaris)
      - CD22 binds B-cell receptor (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
      - LYN phosphorylates CD22 (Canis familiaris)
        
        CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
      - SHP1 binds p-CD22 (Canis familiaris)
        
        PTPN6:p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        Antigen:p-BCR [plasma membrane] (Canis familiaris)
        
        p-BCR [plasma membrane] (Canis familiaris)
        
        IgM or IgD [plasma membrane] (Canis familiaris)
        
        IgD [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)
        
        IgM [plasma membrane] (Canis familiaris)
        
        Immunoglobulin Lambda Light Chain [plasma membrane] (Canis familiaris)
        
        Ig Lamda Light Chain V Region [plasma membrane] (Canis familiaris)
        
        F1Q184 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:F1Q184

Reference Genes

ENSEMBL:ENSCAFG00000031196

Participant Of

hasMember

Ig Lamda Light Chain V Region [plasma membrane]

Other forms of this molecule

F1Q184 [extracellular region]

Inferred From

Ig lambda chain V-IV region Hil [plasma membrane] (Homo sapiens)

Ig lambda chain V-IV region Bau [plasma membrane] (Homo sapiens)

Ig lambda chain V-IV region Kern [plasma membrane] (Homo sapiens)

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