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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Release Calendar
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Our Logo
License Agreement
Privacy Notice
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Digital Preservation
Contact us
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Table of Contents
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COVID-19 Disease Pathways
Docs
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How do I search ?
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FGF19 [extracellular region]
Stable Identifier
R-CFA-189888
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
extracellular region
Synonyms
FGF19, A0A8I3NVV1
Locations in the PathwayBrowser
Expand all
Signal Transduction (Canis familiaris)
Intracellular signaling by second messengers (Canis familiaris)
PIP3 activates AKT signaling (Canis familiaris)
Negative regulation of the PI3K/AKT network (Canis familiaris)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activator:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activator:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
RAS GEFs promote RAS nucleotide exchange (Canis familiaris)
RAS GEFs [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Activated FGFR4:pY-SHC1 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by FGFR (Canis familiaris)
Signaling by FGFR4 (Canis familiaris)
Downstream signaling of activated FGFR4 (Canis familiaris)
FRS-mediated FGFR4 signaling (Canis familiaris)
Activated FGFR4 binds FRS2 (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 binds FRS3 (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 phosphorylates FRS2 (Canis familiaris)
Activated FGFR4:FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-8T-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 phosphorylates FRS3 (Canis familiaris)
Activated FGFR4:FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 phosphorylates PPTN11 (Canis familiaris)
Activated FGFR4:p-FRS:PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS bind to PPTN11 (Canis familiaris)
Activated FGFR4:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS:PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS binds GRB2:SOS1 (Canis familiaris)
Activated FGFR4:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR4:p-FRS:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
PI-3K cascade:FGFR4 (Canis familiaris)
Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Phospholipase C-mediated cascade; FGFR4 (Canis familiaris)
Activated FGFR4 binds PLCG1 (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
activated FGFR4:PLCG1 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 phosphorylates PLCG1 (Canis familiaris)
activated FGFR4:PLCG1 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
p-4Y-PLCG1 dissociates from activated FGFR4 (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
SHC-mediated cascade:FGFR4 (Canis familiaris)
Activated FGFR4 binds SHC1 (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:SHC1 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 phosphorylates SHC1 (Canis familiaris)
Activated FGFR4:SHC1 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:pY-SHC1 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-SHC1 binds GRB2:SOS1 (Canis familiaris)
Activated FGFR4:pY-SHC1 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Activated FGFR4:pY-SHC1 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Activated FGFR4:pY-SHC1 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
FGFR4 ligand binding and activation (Canis familiaris)
Autocatalytic phosphorylation of FGFR4 (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
FGFR4 homodimer bound to FGF [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
FGFR4 binds to FGF (Canis familiaris)
FGFR4 homodimer bound to FGF [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
betaKlotho-mediated ligand binding (Canis familiaris)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
FGFR4:HS:KLB:FGF19 [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
FGFR4 binds HS:KLB:FGF19 (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
FGFR4:HS:KLB:FGF19 [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Negative regulation of FGFR4 signaling (Canis familiaris)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Canis familiaris)
Activated FGFR4:FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-8T-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
CBL ubiquitinates FRS2 and FGFR4 (Canis familiaris)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Ub-Activated FGFR4 complex:Ub-p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Canis familiaris)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Signaling by Insulin receptor (Canis familiaris)
Insulin receptor signalling cascade (Canis familiaris)
IRS-mediated signalling (Canis familiaris)
PI3K Cascade (Canis familiaris)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Canis familiaris)
PI3K-containing complexes [cytosol] (Canis familiaris)
Activated FGFR bound to PI3K [cytosol] (Canis familiaris)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Canis familiaris)
Activated FGFR:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Canis familiaris)
IGF1R signaling cascade (Canis familiaris)
IRS-related events triggered by IGF1R (Canis familiaris)
IRS-mediated signalling (Canis familiaris)
PI3K Cascade (Canis familiaris)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Canis familiaris)
PI3K-containing complexes [cytosol] (Canis familiaris)
Activated FGFR bound to PI3K [cytosol] (Canis familiaris)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Canis familiaris)
Activated FGFR:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
Activated FGFR4 homodimer [plasma membrane] (Canis familiaris)
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
FGF19 [extracellular region] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3NVV1
Gene Names
FGF19
Reference Genes
ENSEMBL:ENSCAFG00845015136.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845015136.1 FGF19
Other Identifiers
483681
CfaAffx.16710.1.S1_at
GO:0001934
GO:0005104
GO:0005576
GO:0006629
GO:0008083
GO:0008284
GO:0008543
GO:0010629
GO:0023052
GO:0036211
GO:0046326
GO:0046330
GO:0048018
GO:0055085
GO:0070374
GO:0070858
GO:0098772
Participates
as an input of
FGFR4 binds HS:KLB:FGF19 (Canis familiaris)
as a component of
FGFR4:HS:KLB:FGF19 [plasma membrane] (Canis familiaris)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Canis familiaris)
as a member of
FGFR4-binding FGFs [extracellular region] (Canis familiaris)
Inferred From
FGF19 [extracellular region]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000162344
Ensembl
ENSCAFG00845015136
,
ENSCAFT00845027035
,
ENSCAFP00845021274
© 2024
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