Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
H2BC2 [nucleoplasm]
Stable Identifier
R-CFA-181916-2
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
HIST1H2BA, A0A8I3S4J6
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle Checkpoints (Canis familiaris)
G2/M Checkpoints (Canis familiaris)
G2/M DNA damage checkpoint (Canis familiaris)
CHEK2 is recruited to DNA DSBs (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex:CHEK2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Phosphorylation and activation of CHEK2 by ATM (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex:CHEK2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Prophase (Canis familiaris)
Condensation of Prophase Chromosomes (Canis familiaris)
CDK1 phosphorylates condensin II subunit NCAPD3 (Canis familiaris)
Condensin II:Nucleosome with H4K20me1 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PHF8 demethylates histone H4K20me1 (Canis familiaris)
PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PLK1 binds phosphorylated condensin II complex (Canis familiaris)
Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PLK1 hyperphosphorylates Condensin II complex (Canis familiaris)
Hyperphosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Chromosome Maintenance (Canis familiaris)
Telomere Maintenance (Canis familiaris)
Inhibition of DNA recombination at telomere (Canis familiaris)
ATRX:DAXX binds to subtelomeric chromosomal regions (Canis familiaris)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] (Canis familiaris)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular Senescence (Canis familiaris)
DNA Damage/Telomere Stress Induced Senescence (Canis familiaris)
Telomere shortening during replicative exhaustion (Canis familiaris)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Oxidative Stress Induced Senescence (Canis familiaris)
KDM6B demethylates H3K27me3 on p16INK4A promoter (Canis familiaris)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K27me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
CDKN2A Gene:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Canis familiaris)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K27me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Canis familiaris)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K27me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Canis familiaris)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K27me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
CDKN2A Gene:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Senescence-Associated Secretory Phenotype (SASP) (Canis familiaris)
EHMT1:EHMT2 methylates IL6 promoter (Canis familiaris)
IL6 gene:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
IL6 gene:Nucleosome-H3K9Me2 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
EHMT1:EHMT2 methylates IL8 promoter (Canis familiaris)
IL8 gene:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
IL8 gene:Nucleosome-H3K9Me2 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Chromatin organization (Canis familiaris)
Chromatin modifying enzymes (Canis familiaris)
HATs acetylate histones (Canis familiaris)
ATF2 acetylates histone H2B, H4 (Canis familiaris)
Histone H2B, H4 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Histone HIST1H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
EP300 acetylates histone H2A, H2B, H3, H4 (Canis familiaris)
Histone H2A, H2B, H3, H4 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Histone HIST1H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
HDACs deacetylate histones (Canis familiaris)
HDAC10 deacetylates histone (Canis familiaris)
Core histone octamer [nucleoplasm] (Canis familiaris)
Histone H2A:H2B [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Histone HIST1H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
HDAC1:2-containing complex deacetylate histones (Canis familiaris)
Core histone octamer [nucleoplasm] (Canis familiaris)
Histone H2A:H2B [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Histone HIST1H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
HDAC3 containing complexes deacetylate histone (Canis familiaris)
Core histone octamer [nucleoplasm] (Canis familiaris)
Histone H2A:H2B [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Histone HIST1H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
HDAC8 deacetylates histones (Canis familiaris)
Core histone octamer [nucleoplasm] (Canis familiaris)
Histone H2A:H2B [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Histone HIST1H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA Repair (Canis familiaris)
Base Excision Repair (Canis familiaris)
Base-Excision Repair, AP Site Formation (Canis familiaris)
Depurination (Canis familiaris)
Cleavage of the damaged purine (Canis familiaris)
NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Canis familiaris)
NEIL3:AP-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
AP-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Recognition and association of DNA glycosylase with site containing an affected purine (Canis familiaris)
NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Canis familiaris)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA Double-Strand Break Repair (Canis familiaris)
DNA Double Strand Break Response (Canis familiaris)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Canis familiaris)
APBB1 and MAPK8 bind diphosphorylated H2AFX (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome:APBB1:p-T,Y-MAPK8 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
ATM phosphorylates EYA1-4 (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
ATM phosphorylates HERC2 (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:HERC2:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+ [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:p-T4827-HERC2:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+ [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
ATM phosphorylates MDC1 (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
ATM phosphorylates TP53BP1 at DNA DSBs (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
ATM phosphorylates WHSC1 (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
ATM phosphorylates histone H2AFX on S139 at DNA DSBs (Canis familiaris)
DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-Y142-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
CHEK2 is recruited to DNA DSBs (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex:CHEK2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
CHEK2 phosphorylates BRCA1 (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-5S,2T-BRCA1-A complex [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
EYA1-4 dephosphorylates tyrosine Y142 of H2AFX (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Formation of BRCA1-A complex at DNA DSBs (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:BRCA1-A complex [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:UIMC1:p-S406-FAM175A [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
HERC2 and PIAS4 are recruited to DNA DSBs (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+ [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:HERC2:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+ [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
KDM4A,B bind H4K20Me2 (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
MDC1 associates with gamma-H2AFX at nuclear foci (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PPP5C dephosphorylates TP53BP1 (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Phosphorylation and activation of CHEK2 by ATM (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex:CHEK2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Phosphorylation of BRCA1-A complex at multiple sites by ATM (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:BRCA1-A complex [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
RNF168 binds DNA DSBs (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
RNF8 and RNF168 ubiquitinate H2AFX (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
RNF8 and RNF168 ubiquitinate KDM4A,B (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
TP53BP1 associates with H4K20Me2 at DNA DSBs (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
UIMC1 and FAM175A bind DNA DSBs (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:UIMC1:p-S406-FAM175A [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
WHSC1 binds DNA DSBs (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Nonhomologous End-Joining (NHEJ) (Canis familiaris)
Activated ATM phosphorylates DCLRE1C (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:RIF1:PAX1IP:DCLRE1C [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:RIF1:PAXIP1 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:RIF1:PAXIP1 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
RIF1 and PAX1IP bind TP53BP1 at DNA DSBs (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:RIF1:PAXIP1 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-5S,2T-BRCA1-A complex [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
TP53BP1 recruits DCLRE1C to ATM (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:RIF1:PAX1IP:DCLRE1C [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:RIF1:PAXIP1 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:RIF1:PAXIP1 [nucleoplasm] (Canis familiaris)
DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1 [nucleoplasm] (Canis familiaris)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNA Replication (Canis familiaris)
DNA Replication Pre-Initiation (Canis familiaris)
Assembly of the pre-replicative complex (Canis familiaris)
Assembly of the ORC complex at the origin of replication (Canis familiaris)
ORC1 binds to H4K20me2 (Canis familiaris)
H4K20Me2-nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
ORC1:H4K20Me2-nucleosome [nucleoplasm] (Canis familiaris)
H4K20Me2-nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Gene expression (Transcription) (Canis familiaris)
Epigenetic regulation of gene expression (Canis familiaris)
Negative epigenetic regulation of rRNA expression (Canis familiaris)
NoRC negatively regulates rRNA expression (Canis familiaris)
MBD2 binds methylcytosine in chromatin (Canis familiaris)
Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Canis familiaris)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
SIRT1 negatively regulates rRNA expression (Canis familiaris)
Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
eNoSC [nucleoplasm] (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
eNoSC deacetylates histone H3 (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Chromatin with acetylated H3 [nucleoplasm] (Canis familiaris)
Nucleosome (H3K9ac, H3K14ac) [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
eNoSC [nucleoplasm] (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
eNoSC dimethylates histone H3 at lysine-9 (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
eNoSC [nucleoplasm] (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PRC2 methylates histones and DNA (Canis familiaris)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Canis familiaris)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Canis familiaris)
PRC2:Chromatin (5-methylcytosine, H3K27me3) [nucleoplasm] (Canis familiaris)
Chromatin with hemimethylC, H3K27me3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K27me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Canis familiaris)
PRC2 Core:Chromatin [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PRC2 recruits DNA methyltransferases (Canis familiaris)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Canis familiaris)
PRC2 Core:Chromatin [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PRC2 Core:Chromatin [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PRC2 trimethylates histone H3 at lysine-27 (Canis familiaris)
PRC2:Chromatin (H3K27me3) [nucleoplasm] (Canis familiaris)
Chromatin with trimethylated H3K27 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K27me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PRC2:Chromatin [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PRC2:Chromatin [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Positive epigenetic regulation of rRNA expression (Canis familiaris)
B-WICH complex positively regulates rRNA expression (Canis familiaris)
B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 (Canis familiaris)
Nucleosome (H3K9ac) [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Gene Silencing by RNA (Canis familiaris)
Transcriptional regulation by small RNAs (Canis familiaris)
AGO1,2:small RNA complexes interact with chromatin (Canis familiaris)
AGO1,2:miRNA:chromatin:RNA pol II [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
RNA Polymerase I Transcription (Canis familiaris)
RNA Polymerase I Promoter Clearance (Canis familiaris)
RNA Polymerase I Promoter Escape (Canis familiaris)
Elongation of pre-rRNA transcript (Canis familiaris)
Chromatin (H3K9me2):CBX3 [nucleoplasm] (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
RNA Polymerase I Promoter Opening (Canis familiaris)
UBF-1 Binds rDNA Promoter (Canis familiaris)
Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Canis familiaris)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional regulation by RUNX1 (Canis familiaris)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Canis familiaris)
H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Canis familiaris)
H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Canis familiaris)
H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Canis familiaris)
H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Deubiquitination (Canis familiaris)
Ub-specific processing proteases (Canis familiaris)
USP3,SAGA deubiquitinate Histone H2A,H2B (Canis familiaris)
USP3,SAGA:Histone H2A,Histone H2B [nucleoplasm] (Canis familiaris)
Histone H2A,Histone H2B [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Histone HIST1H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
USP49 deubiquitinates H2B (Canis familiaris)
USP49:Histone H2B [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Histone HIST1H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Protein ubiquitination (Canis familiaris)
E3 ubiquitin ligases ubiquitinate target proteins (Canis familiaris)
RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B (Canis familiaris)
Histone HIST1H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PAF1c:WAC:RNF20:RNF40:Ub:UBE2A,B:HIST1H2B [nucleoplasm] (Canis familiaris)
Histone HIST1H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
RNF20:RNF40 monoubiquitinates Histone H2B (Canis familiaris)
PAF1c:WAC:RNF20:RNF40:Ub:UBE2A,B:HIST1H2B [nucleoplasm] (Canis familiaris)
Histone HIST1H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
ESR-mediated signaling (Canis familiaris)
Estrogen-dependent gene expression (Canis familiaris)
Binding of AP1 transcriptional activator complexes to CCND1 promoter (Canis familiaris)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3:ESTG:ESR1 dimer:JUN:ATF2:POUF21:ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] (Canis familiaris)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
EP300 is recruited to MYC and BCL2 genes (Canis familiaris)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
HIST1H2AC nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG:EP300 [nucleoplasm] (Canis familiaris)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
HIST1H2AC nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Canis familiaris)
KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Canis familiaris)
KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
FOXA1 and GATA3 bind to CCND1 promoter (Canis familiaris)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Canis familiaris)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Canis familiaris)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
HIST1H2AC nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
KDM1A is recruited to MYC and BCL2 genes (Canis familiaris)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Canis familiaris)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Canis familiaris)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Canis familiaris)
KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
KDM4B-regulated genes:nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
NR5A2, ZNF217 and NCOA3 bind GREB1 promoter (Canis familiaris)
GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
GREB1 gene:nucleosome:ESR1:ESTG:ZNF217:NCOA3:NR5A2 [nucleoplasm] (Canis familiaris)
GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Canis familiaris)
MYC gene, BCL2 gene: H3K9me2 nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases activate PKNs (Canis familiaris)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Canis familiaris)
Demethylase KDM1A binds KLK2 and KLK3 promoters (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
Demethylase KDM4C binds KLK2 and KLK3 promoters (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Canis familiaris)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Canis familiaris)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12-H3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Canis familiaris)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Canis familiaris)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Canis familiaris)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Canis familiaris)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Canis familiaris)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me3 [nucleoplasm] (Canis familiaris)
Histone H2B [nucleoplasm] (Canis familiaris)
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
H2BC2 [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3S4J6
Gene Names
H2BC2
Reference Genes
ENSEMBL:ENSCAFG00845024354.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845024354.1 H2BC2
Reference Transcript
RefSeq:XM_005640107.2 H2BC2
Other Identifiers
488252
488253
CfaAffx.287.1.S1_at
CfaAffx.791.1.S1_s_at
GO:0000786
GO:0003677
GO:0005198
GO:0005634
GO:0005694
GO:0030527
GO:0043226
GO:0046982
Participates
as a member of
Homologues of HIST1H2BA [nucleoplasm] (Canis familiaris)
Other forms of this molecule
H2BC2 [nucleoplasm]
H2BC2 [nucleoplasm]
H2BC2 [nucleoplasm]
H2BC2 [nucleoplasm]
H2BC2 [nucleoplasm]
H2BC2 [nucleoplasm]
Inferred From
HIST1H2BA [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_005640164.1
Ensembl
ENSCAFG00845024354
,
ENSCAFP00845033719
,
ENSCAFT00845043007
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
