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TGFB1: p-TGFBR: I-SMAD7 [plasma membrane]
Stable Identifier
R-CFA-173476
Type
Complex
Species
Canis familiaris
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Canis familiaris)
Signaling by TGFB family members (Canis familiaris)
Signaling by TGF-beta Receptor Complex (Canis familiaris)
TGF-beta receptor signaling activates SMADs (Canis familiaris)
Downregulation of TGF-beta receptor signaling (Canis familiaris)
Degradation of TGF-beta receptor complex (Canis familiaris)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Canis familiaris)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Canis familiaris)
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Canis familiaris)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
SMAD7 [cytosol]
(Canis familiaris)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane]
(Canis familiaris)
Participates
as a component of
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Canis familiaris)
as an output of
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Canis familiaris)
Inferred From
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane]
(Homo sapiens)
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