Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-MAPK12 [cytosol]
Stable Identifier
R-CFA-171021
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
p-T183,Y185-MAPK12, A0A8I3ND88
Locations in the PathwayBrowser
Expand all
Developmental Biology (Canis familiaris)
Myogenesis (Canis familiaris)
Nuclear translocation of p38 MAPK (Canis familiaris)
pp38 alpha/beta/gamma:ABL1:JLP:CDO complex [plasma membrane] (Canis familiaris)
Phospho-p38 MAPK alpha/beta/gamma [cytosol] (Canis familiaris)
phospho-MAPK12 [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Innate Immune System (Canis familiaris)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Canis familiaris)
NOD1/2 Signaling Pathway (Canis familiaris)
Activation of p38 MAPK (Canis familiaris)
Phospho-p38 MAPK [cytosol] (Canis familiaris)
phospho-MAPK12 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
Negative regulation of MAPK pathway (Canis familiaris)
MAPK12 phosphorylates PTPN3 (Canis familiaris)
PTPN3:p-T183,Y185-MAPK12 [cytosol] (Canis familiaris)
phospho-MAPK12 [cytosol] (Canis familiaris)
p-S459 PTPN3:p-T183,Y185-MAPK12 [cytosol] (Canis familiaris)
phospho-MAPK12 [cytosol] (Canis familiaris)
PTPN3 binds p-T183,Y185 MAPK12 (Canis familiaris)
PTPN3:p-T183,Y185-MAPK12 [cytosol] (Canis familiaris)
phospho-MAPK12 [cytosol] (Canis familiaris)
phospho-MAPK12 [cytosol] (Canis familiaris)
PTPN3 dephosphorylates MAPK12 (Canis familiaris)
PTPN3:p-T183,Y185-MAPK12 [cytosol] (Canis familiaris)
phospho-MAPK12 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3ND88
Gene Names
MAPK12
Reference Genes
ENSEMBL:ENSCAFG00845005996.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845005996.1 MAPK12
Other Identifiers
607023
CfaAffx.1957.1.S1_at
GO:0000165
GO:0000166
GO:0000287
GO:0003824
GO:0004672
GO:0004674
GO:0004707
GO:0005524
GO:0006468
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0030154
GO:0036211
GO:0045445
GO:0048856
GO:0140096
Participates
as a member of
Phospho-p38 MAPK alpha/beta/gamma [cytosol] (Canis familiaris)
as a component of
p-S459 PTPN3:p-T183,Y185-MAPK12 [cytosol] (Canis familiaris)
PTPN3:p-T183,Y185-MAPK12 [cytosol] (Canis familiaris)
as an input of
PTPN3 binds p-T183,Y185 MAPK12 (Canis familiaris)
as a candidate of
Phospho-p38 MAPK [cytosol] (Canis familiaris)
Other forms of this molecule
MAPK12 [nucleoplasm]
MAPK12 [cytosol]
Inferred From
p-T183,Y185-MAPK12 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 183 (in Homo sapiens)
Coordinate
183
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O4'-phospho-L-tyrosine at 185 (in Homo sapiens)
Coordinate
185
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
OpenTargets
ENSG00000188130
Ensembl
ENSCAFT00845010789
,
ENSCAFG00845005996
,
ENSCAFP00845008421
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text