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What is Reactome ?
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PPP2R5E [cytosol]
Stable Identifier
R-CFA-1638770
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
PPP2R5E, A0A8I3RRJ5
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle Checkpoints (Canis familiaris)
Mitotic Spindle Checkpoint (Canis familiaris)
Amplification of signal from the kinetochores (Canis familiaris)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Canis familiaris)
MAD2 associates with the Mad1 kinetochore complex (Canis familiaris)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
MAD2 converted to an inhibitory state via interaction with Mad1 (Canis familiaris)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Mad1 binds kinetochore (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Release of activated MAD2 from kinetochores (Canis familiaris)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Metaphase and Anaphase (Canis familiaris)
Mitotic Anaphase (Canis familiaris)
Separation of Sister Chromatids (Canis familiaris)
ESPL1 (Separase) cleaves centromeric cohesin (Canis familiaris)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Separation of sister chromatids (Canis familiaris)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Mitotic Prometaphase (Canis familiaris)
EML4 and NUDC in mitotic spindle formation (Canis familiaris)
EML4 recruits NUDC to mitotic spindle (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Kinetochore capture of astral microtubules (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Resolution of Sister Chromatid Cohesion (Canis familiaris)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Canis familiaris)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Kinetochore assembly (Canis familiaris)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
PP2A-B56 dephosphorylates centromeric cohesin (Canis familiaris)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Phosphorylation of cohesin by PLK1 at centromeres (Canis familiaris)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Hemostasis (Canis familiaris)
Platelet homeostasis (Canis familiaris)
Platelet sensitization by LDL (Canis familiaris)
PECAM-1 binds PP2A (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
p-PECAM:PP2A [plasma membrane] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Costimulation by the CD28 family (Canis familiaris)
CTLA4 inhibitory signaling (Canis familiaris)
CTLA-4 binds B7-1/B7-2 (Canis familiaris)
CTLA4 dimer:PP2A [plasma membrane] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
PP2A:CTLA4:B7-1/B7-2 [plasma membrane] (Canis familiaris)
CTLA4 dimer:PP2A [plasma membrane] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
PP2A binds CTLA4 dimer (Canis familiaris)
CTLA4 dimer:PP2A [plasma membrane] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Phosphorylation of CTLA-4 (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
PP2A:CTLA4:B7-1/B7-2 [plasma membrane] (Canis familiaris)
CTLA4 dimer:PP2A [plasma membrane] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Intracellular signaling by second messengers (Canis familiaris)
PIP3 activates AKT signaling (Canis familiaris)
Negative regulation of the PI3K/AKT network (Canis familiaris)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Canis familiaris)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
p-Y307-PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
Negative regulation of MAPK pathway (Canis familiaris)
PP2A dephosphorylates RAF1 (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases Activate Formins (Canis familiaris)
AURKB phosphorylates DIAPH2-2 at kinetochores (Canis familiaris)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
CDC42:GTP recruits DIAPH2-2 to kinetochores (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Signaling by WNT (Canis familiaris)
Degradation of beta-catenin by the destruction complex (Canis familiaris)
AXIN is phosphorylated in the destruction complex (Canis familiaris)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Assembly of the destruction complex (Canis familiaris)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Canis familiaris)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Canis familiaris)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Association of beta-catenin with the destruction complex (Canis familiaris)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Beta-catenin phosphorylation cascade (Canis familiaris)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Canis familiaris)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Canis familiaris)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Canis familiaris)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Canis familiaris)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Degradation of ubiquitinated beta catenin by the proteasome (Canis familiaris)
p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Canis familiaris)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Canis familiaris)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Canis familiaris)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Canis familiaris)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Canis familiaris)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Canis familiaris)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Canis familiaris)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
Phosphorylation of APC component of the destruction complex (Canis familiaris)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
TCF dependent signaling in response to WNT (Canis familiaris)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Canis familiaris)
Beta-catenin is released from the destruction complex (Canis familiaris)
CTNNB1:AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
PP2A [cytosol] (Canis familiaris)
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
PPP2R5E [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3RRJ5
Gene Names
PPP2R5E
Reference Genes
ENSEMBL:ENSCAFG00845001510.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845001510.1 PPP2R5E
Other Identifiers
480349
Cfa.1638.1.A1_at
Cfa.20148.1.S1_s_at
GO:0000159
GO:0005829
GO:0007165
GO:0019888
GO:0023052
GO:0098772
Participates
as a candidate of
PP2A regulatory subunit B56 [cytosol] (Canis familiaris)
Inferred From
PPP2R5E [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000154001
Ensembl
ENSCAFP00845002076
,
ENSCAFG00845001510
,
ENSCAFT00845002609
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