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H3C6 [nucleoplasm]
Stable Identifier
R-CFA-1214186
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
Me3K5-HIST1H3A, J9PB22
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Prophase (Canis familiaris)
Condensation of Prophase Chromosomes (Canis familiaris)
CDK1 phosphorylates PHF8 (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
CDK1 phosphorylates condensin II subunit NCAPD3 (Canis familiaris)
Condensin II:Nucleosome with H4K20me1 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
Condensin II complex binds H4K20me1-containing nucleosomes (Canis familiaris)
Condensin II:Nucleosome with H4K20me1 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
PHF8 demethylates histone H4K20me1 (Canis familiaris)
PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
PLK1 binds phosphorylated condensin II complex (Canis familiaris)
Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
PLK1 hyperphosphorylates Condensin II complex (Canis familiaris)
Hyperphosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
SETD8 monomethylates histone H4 (Canis familiaris)
PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
H3K4me2/3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
Chromatin organization (Canis familiaris)
Chromatin modifying enzymes (Canis familiaris)
HATs acetylate histones (Canis familiaris)
KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
HDMs demethylate histones (Canis familiaris)
KDM5A-D demethylate Me3K5-histone H3 (Canis familiaris)
Me3K5-histone H3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
PKMTs methylate histone lysines (Canis familiaris)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Canis familiaris)
Me3K5-histone H3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional regulation by RUNX1 (Canis familiaris)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Canis familiaris)
H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me3 [nucleoplasm] (Canis familiaris)
Histone H3 (H3K4me3) [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Canis familiaris)
H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me3 [nucleoplasm] (Canis familiaris)
Histone H3 (H3K4me3) [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Canis familiaris)
H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me3 [nucleoplasm] (Canis familiaris)
Histone H3 (H3K4me3) [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Canis familiaris)
H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me3 [nucleoplasm] (Canis familiaris)
Histone H3 (H3K4me3) [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by WNT (Canis familiaris)
TCF dependent signaling in response to WNT (Canis familiaris)
Formation of the beta-catenin:TCF transactivating complex (Canis familiaris)
SET1 complex trimethylates H3K4 at the MYC gene (Canis familiaris)
MYC gene:H2B K121ub H3K4me3 nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H2BK121ub and H3K4me3 [nucleoplasm] (Canis familiaris)
H3K4me3 [nucleoplasm] (Canis familiaris)
H3C6 [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:J9PB22
Gene Names
H3C6
Reference Genes
BioGPS Gene:106558266 H3C6
BioGPS Gene:488263 H3C6
ENSEMBL:ENSCAFG00000029173
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000040996 H3C6
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000042995 H3C6
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000043815 H3C6
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000045512 H3C6
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000045750 H3C6
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000048378 H3C6
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000048797 H3C6
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000049134 H3C6
KEGG Gene (Canis lupus familiaris):106558266 H3C6
KEGG Gene (Canis lupus familiaris):488263 H3C6
Monarch:106558266 H3C6
Monarch:488263 H3C6
NCBI Gene:106558266 H3C6
NCBI Gene:488263 H3C6
Reference Transcript
RefSeq:XM_014110640.1 H3C6
RefSeq:XM_014110602.1 H3C6
RefSeq:XM_005640101.2 H3C6
RefSeq:XM_849194.4 H3C6
RefSeq:XM_014110523.1 H3C6
Other Identifiers
100855507
106557493
106558262
106558266
111093988
115945163
115945196
115945198
488263
611519
CfaAffx.945.1.S1_s_at
GO:0000228
GO:0000786
GO:0000788
GO:0003674
GO:0003677
GO:0005575
GO:0005622
GO:0005634
GO:0005694
GO:0006334
GO:0006335
GO:0008150
GO:0022607
GO:0032991
GO:0043226
GO:0046982
GO:0051276
GO:0060968
GO:0065003
Participant Of
input
KAT7-containing ING4/5 complexes acetylate Me3K-histone H3
hasCandidate
H3K4me3 [nucleoplasm]
Me3K5-histone H3 [nucleoplasm]
hasMember
Histone H3 (H3K4me3) [nucleoplasm]
Other forms of this molecule
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
phospho-H3C6 [nucleoplasm]
phospho-H3C6 [nucleoplasm]
phospho-H3C6 [nucleoplasm]
phospho-H3C6 [nucleoplasm]
phospho-H3C6 [nucleoplasm]
phospho-H3C6 [nucleoplasm]
phospho-H3C6 [nucleoplasm]
phospho-H3C6 [nucleoplasm]
phospho-H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [cytosol]
H3C6 [cytosol]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
phospho-H3C6 [nucleoplasm]
phospho-H3C6 [nucleoplasm]
phospho-H3C6 [nucleoplasm]
phospho-H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
H3C6 [nucleoplasm]
Inferred From
Me3K5-HIST1H3A [nucleoplasm] (Homo sapiens)
Me3K-histone H3 [nucleoplasm] (Homo sapiens)
Me3K5-HIST3H3 [nucleoplasm] (Homo sapiens)
Modified Residues
Name
N6,N6,N6-trimethyl-L-lysine at 5 (in Homo sapiens)
Coordinate
5
PsiMod Name
N6,N6,N6-trimethyl-L-lysine [MOD:00083]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6,N6,N6-trimethyl-L-lysine.
Cross References
RefSeq
XP_854287.2
,
XP_013966115.1
,
XP_013966077.1
,
XP_005640158.1
,
XP_013965998.1
Target Pathogen
5b2801b3be737e35a6df0ddc
,
57c08b76be737e1cc0a95c6a
,
5b2801b2be737e35a6de88ae
,
5b2801b3be737e35a6df0ac2
,
5b2801b3be737e35a6df1873
,
5b2801b3be737e35a6df0c8a
,
5b354852be737e166372eb9b
,
5b2801b2be737e35a6dea9b5
,
5b2801b2be737e35a6dea64d
,
5b2801b3be737e35a6dee562
,
5b354852be737e166372eaa2
,
5b354852be737e166372e957
,
57c0ab9bbe737e1cc0a9d7f0
,
5b354852be737e166372e85a
,
57c5e634be737e5a0cb4cb11
,
5b2801b2be737e35a6de9484
,
57c0aa24be737e1cc0a9c2e3
,
5b2801b2be737e35a6dea8d6
,
57c0ab45be737e1cc0a9d2f0
,
5b2801b3be737e35a6deea80
,
5b354852be737e166372eaa9
,
57cdcfdfbe737e0b49b9a3bb
,
57c5eaa7be737e5a0cb4f982
OpenTargets
ENSG00000274750
Ensembl
ENSCAFT00000077940
,
ENSCAFG00000045512
,
ENSCAFG00000042995
,
ENSCAFG00000040996
,
ENSCAFT00000078772
,
ENSCAFT00000074659
,
ENSCAFP00000051473
,
ENSCAFP00000051615
,
ENSCAFT00000080570
,
ENSCAFG00000048797
,
ENSCAFT00000068032
,
ENSCAFT00000078478
,
ENSCAFP00000053496
,
ENSCAFT00000074047
,
ENSCAFG00000048378
,
ENSCAFP00000043669
,
ENSCAFG00000049134
,
ENSCAFG00000045750
,
ENSCAFG00000043815
,
ENSCAFP00000060440
,
ENSCAFP00000062267
,
ENSCAFT00000088512
,
ENSCAFP00000060218
,
ENSCAFP00000045302
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