Reactome | H3C6 [nucleoplasm]

H3C6 [nucleoplasm]

Stable Identifier

R-CFA-1214186

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

Me3K5-HIST1H3A, J9PB22

Locations in the PathwayBrowser

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Signal Transduction (Canis familiaris)

- Signaling by WNT (Canis familiaris)
  - TCF dependent signaling in response to WNT (Canis familiaris)
    - Formation of the beta-catenin:TCF transactivating complex (Canis familiaris)
      - SET1 complex trimethylates H3K4 at the MYC gene (Canis familiaris)
        
        MYC gene:H2B K121ub H3K4me3 nucleosome [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H2BK121ub and H3K4me3 [nucleoplasm] (Canis familiaris)
        
        H3K4me3 [nucleoplasm] (Canis familiaris)
        
        H3C6 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:J9PB22

Gene Names

H3C6

Reference Genes

BioGPS Gene:106558266 H3C6

BioGPS Gene:488263 H3C6

ENSEMBL:83716

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000040996 H3C6

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000042995 H3C6

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000043815 H3C6

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000045512 H3C6

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000045750 H3C6

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000048378 H3C6

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000048797 H3C6

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000049134 H3C6

KEGG Gene (Canis lupus familiaris):106558266 H3C6

KEGG Gene (Canis lupus familiaris):488263 H3C6

Monarch:106558266 H3C6

Monarch:488263 H3C6

NCBI Gene:106558266 H3C6

NCBI Gene:488263 H3C6

Reference Transcript

Other Identifiers

100855507

106557493

106558262

106558266

111093988

115945163

115945196

115945198

488263

611519

CfaAffx.945.1.S1_s_at

GO:0000228

GO:0000786

GO:0003674

GO:0003677

GO:0005575

GO:0005622

GO:0005634

GO:0005694

GO:0006334

GO:0006335

GO:0008150

GO:0022607

GO:0032991

GO:0043226

GO:0046982

GO:0051276

GO:0060968

GO:0065003

Participates

as an input of

KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 (Canis familiaris)

as a candidate of

as a member of

Histone H3 (H3K4me3) [nucleoplasm] (Canis familiaris)

Other forms of this molecule

H3C6 [nucleoplasm]

phospho-H3C6 [nucleoplasm]

H3C6 [nucleoplasm]

H3C6 [cytosol]

H3C6 [nucleoplasm]

phospho-H3C6 [nucleoplasm]

H3C6 [nucleoplasm]

Inferred From

Me3K-histone H3 [nucleoplasm] (Homo sapiens)

Me3K5-HIST1H3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6,N6,N6-trimethyl-L-lysine at 5 (in Homo sapiens)

Coordinate

PsiMod Name

N6,N6,N6-trimethyl-L-lysine [MOD:00083]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6,N6,N6-trimethyl-L-lysine.

Cross References

RefSeq

XP_013965998.1, XP_013966115.1, XP_005640158.1, XP_013966077.1, XP_854287.2

OpenTargets

ENSG00000274750

Ensembl

ENSCAFT00000078772, ENSCAFT00000074659, ENSCAFG00000045512, ENSCAFT00000078478, ENSCAFP00000060440, ENSCAFT00000077940, ENSCAFP00000060218, ENSCAFG00000042995, ENSCAFG00000040996, ENSCAFP00000062267, ENSCAFP00000051615, ENSCAFT00000088512, ENSCAFP00000051473, ENSCAFT00000080570, ENSCAFP00000053496, ENSCAFP00000043669, ENSCAFP00000045302, ENSCAFT00000074047, ENSCAFG00000048378, ENSCAFT00000068032, ENSCAFG00000048797, ENSCAFG00000049134, ENSCAFG00000043815, ENSCAFG00000045750

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