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phospho-NFKBIE [cytosol]
Stable Identifier
R-CFA-1168563
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
p-S157,S161-Ub-NFKBIE, A0A8I3N908
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Signaling by the B Cell Receptor (BCR) (Canis familiaris)
Downstream signaling events of B Cell Receptor (BCR) (Canis familiaris)
Activation of NF-kappaB in B cells (Canis familiaris)
SCF-beta-TrCP ubiquitinylates IkB (Canis familiaris)
NF-kappaB p50,p65,c-Rel:ub-p-IKB [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel:ub-p-IKB [cytosol] (Canis familiaris)
ub-p-IKB alpha,beta,epsilon [cytosol] (Canis familiaris)
phospho-NFKBIE [cytosol] (Canis familiaris)
NF-kappaB p50:p65:ub-p-IKB [cytosol] (Canis familiaris)
ub-p-IKB alpha,beta,epsilon [cytosol] (Canis familiaris)
phospho-NFKBIE [cytosol] (Canis familiaris)
NF-kappaB p65:p65:ub-p-IkB [cytosol] (Canis familiaris)
phospho-NFKBIE [cytosol] (Canis familiaris)
Ubiquitinated IkB is degraded (Canis familiaris)
NF-kappaB p50,p65,c-Rel:ub-p-IKB [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel:ub-p-IKB [cytosol] (Canis familiaris)
ub-p-IKB alpha,beta,epsilon [cytosol] (Canis familiaris)
phospho-NFKBIE [cytosol] (Canis familiaris)
NF-kappaB p50:p65:ub-p-IKB [cytosol] (Canis familiaris)
ub-p-IKB alpha,beta,epsilon [cytosol] (Canis familiaris)
phospho-NFKBIE [cytosol] (Canis familiaris)
NF-kappaB p65:p65:ub-p-IkB [cytosol] (Canis familiaris)
phospho-NFKBIE [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3N908
Gene Names
NFKBIE
Reference Genes
ENSEMBL:ENSCAFG00845011706.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845011706.1 NFKBIE
Other Identifiers
102155642
CfaAffx.3896.1.S1_at
GO:0001650
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005829
GO:0043226
Participates
as a member of
ub-p-IKB alpha,beta,epsilon [cytosol] (Canis familiaris)
as a component of
NF-kappaB p65:p65:ub-p-IkB [cytosol] (Canis familiaris)
Other forms of this molecule
NFKBIE [cytosol]
phospho-NFKBIE [cytosol]
Inferred From
p-S157,S161-Ub-NFKBIE [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 157 (in Homo sapiens)
Coordinate
157
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 161 (in Homo sapiens)
Coordinate
161
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at unknown position
Modification
K48polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
OpenTargets
ENSG00000146232
Ensembl
ENSCAFP00845016291
,
ENSCAFT00845020768
,
ENSCAFG00845011706
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