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phospho-p-S218,S222-MAP2K1 [cytosol]
Stable Identifier
R-CFA-109837
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
J9P5W6
Locations in the PathwayBrowser
Expand all
Developmental Biology (Canis familiaris)
Axon guidance (Canis familiaris)
L1CAM interactions (Canis familiaris)
Signal transduction by L1 (Canis familiaris)
MAP2K1 phosphorylates MAPK3 (Canis familiaris)
p-2S-MAP2K1:MAPK3 [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-T,Y-MAPK3:p-2S-MAP2K1 [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
FLT3 Signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
MAP2K and MAPK activation (Canis familiaris)
Dissociation of RAS:RAF complex (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
IL17RD binds p-2S MAP2Ks and MAPKs (Canis familiaris)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Canis familiaris)
WDR83:LAMTOR2:LAMTOR3:activated RAF:p-2S MAP2K:p-T,Y MAPK complex [endosome membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Canis familiaris)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
IL17RD:p-2S MAP2Ks:p-T,Y MAPKs [Golgi membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
MAP2Ks phosphorylate MAPKs (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
RAF phosphorylates MAP2K dimer (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
Negative regulation of MAPK pathway (Canis familiaris)
Negative feedback regulation of MAPK pathway (Canis familiaris)
Activated MAPKs phosphorylate MAP2K1 (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
RAF activation (Canis familiaris)
Phosphorylation of RAF (Canis familiaris)
RAF activating kinases [plasma membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF-independent MAPK1/3 activation (Canis familiaris)
MAPK3 (ERK1) activation (Canis familiaris)
Dissociation of p-T,Y-MAPK3:MAP2K1 (Canis familiaris)
p-T,Y-MAPK3:p-2S-MAP2K1 [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
Inactivation of MAP2K1 by CDK1 (Canis familiaris)
MAP2K1 [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
MAP2K1 binds MAPK3 (Canis familiaris)
p-2S-MAP2K1:MAPK3 [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
MAP2K1 phosphorylates MAPK3 (Canis familiaris)
p-2S-MAP2K1:MAPK3 [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-T,Y-MAPK3:p-2S-MAP2K1 [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
MAP2K and MAPK activation (Canis familiaris)
Dissociation of RAS:RAF complex (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
IL17RD binds p-2S MAP2Ks and MAPKs (Canis familiaris)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Canis familiaris)
WDR83:LAMTOR2:LAMTOR3:activated RAF:p-2S MAP2K:p-T,Y MAPK complex [endosome membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Canis familiaris)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
IL17RD:p-2S MAP2Ks:p-T,Y MAPKs [Golgi membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
MAP2Ks phosphorylate MAPKs (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
RAF phosphorylates MAP2K dimer (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
Negative regulation of MAPK pathway (Canis familiaris)
Negative feedback regulation of MAPK pathway (Canis familiaris)
Activated MAPKs phosphorylate MAP2K1 (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
RAF activation (Canis familiaris)
Phosphorylation of RAF (Canis familiaris)
RAF activating kinases [plasma membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by NTRKs (Canis familiaris)
Signaling by NTRK1 (TRKA) (Canis familiaris)
Signalling to ERKs (Canis familiaris)
Prolonged ERK activation events (Canis familiaris)
Frs2-mediated activation (Canis familiaris)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Canis familiaris)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
Dissociation of phosphorylated MAP2Ks and MAPKs (Canis familiaris)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Canis familiaris)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Canis familiaris)
p-2S MAP2K homo/heterodimers [cytosol] (Canis familiaris)
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
p-S218,S222 MAP2K1 dimer [cytosol] (Canis familiaris)
phospho-p-S218,S222-MAP2K1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:J9P5W6
Reference Genes
BioGPS Gene:478347
dbSNP Gene:478347
ENSEMBL:ENSCAFG00000017298
KEGG Gene (Canis familiaris):478347
Monarch:478347
NCBI Gene:478347
Reference Transcript
RefSeq:NM_001048094.2
Other Identifiers
478347
AAEX03016228
Cfa.1354.1.A1_at
Cfa.13955.1.A1_at
CfaAffx.26470.1.S1_s_at
ENSCAFG00000017298
ENSCAFP00000041046
ENSCAFT00000043934
EntrezGene:478347
EntrezGene:MAP2K1
F1PJI7
GO:0000003
GO:0000166
GO:0000187
GO:0000902
GO:0002376
GO:0003674
GO:0004672
GO:0004674
GO:0004708
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005783
GO:0005829
GO:0005886
GO:0006464
GO:0006468
GO:0006950
GO:0007049
GO:0007050
GO:0007165
GO:0007507
GO:0007568
GO:0008022
GO:0008150
GO:0008283
GO:0008285
GO:0009058
GO:0009790
GO:0010628
GO:0010629
GO:0016301
GO:0018107
GO:0021697
GO:0023014
GO:0030154
GO:0030182
GO:0030216
GO:0030234
GO:0030878
GO:0031098
GO:0032147
GO:0034641
GO:0040011
GO:0043167
GO:0043226
GO:0043539
GO:0045597
GO:0045893
GO:0047485
GO:0048538
GO:0048646
GO:0048679
GO:0048856
GO:0048870
GO:0050772
GO:0060020
GO:0060324
GO:0060425
GO:0060440
GO:0060502
GO:0060674
GO:0060711
GO:0070371
GO:0070374
GO:0071902
GO:0090398
GO:0097110
GO:1903800
IPR000719
IPR008271
IPR011009
IPR017441
MAP2K1
MAP2K1-201
PF00069
SM00220
UPI00004BF1A9
VGNC:42960
Participant Of
hasComponent
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol]
p-2S-MAP2K1:MAPK3 [cytosol]
p-S218,S222 MAP2K1 dimer [cytosol]
p-T,Y-MAPK3:p-2S-MAP2K1 [cytosol]
output
Dissociation of p-T,Y-MAPK3:MAP2K1
input
MAP2K1 binds MAPK3
hasMember
MAP2K1 [cytosol]
Other forms of this molecule
phospho-p-S,218, S222,T292 MAP2K1 [cytosol]
phospho-p-T286,T292-MAP2K1 [cytosol]
phospho-p-S218,S222,T286,T292-MAP2K1 [cytosol]
MAP2K1 [cytosol]
Inferred From
p-S218,S222-MAP2K1 [cytosol] (Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 218 (in Homo sapiens)
Coordinate
218
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 222 (in Homo sapiens)
Coordinate
222
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_001041559.2
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