Reactome | vha-16 [lysosomal membrane]

vha-16 [lysosomal membrane]

Stable Identifier

R-CEL-9640177

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

lysosomal membrane

Synonyms

ATP6V0D1, Q95YD5

Locations in the PathwayBrowser

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Cellular responses to external stimuli (Caenorhabditis elegans)

- Cellular responses to stress (Caenorhabditis elegans)
  - Amino acids regulate mTORC1 (Caenorhabditis elegans)
    - RRAGA,B exchanges GDP for GTP (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
    - RRAGA,B hydrolyzes GTP (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
    - RRAGC,D exchanges GTP for GDP (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
    - RRAGC,D hydrolyzes GTP (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
    - mTORC1 binds RHEB:GTP (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
    - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
    - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
    - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-16 [lysosomal membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q95YD5

Gene Names

vha-16

Reference Genes

BioGPS Gene:172134 vha-16

CTD Gene:172134 vha-16

ENSEMBL:WBGene00016258

KEGG Gene (Caenorhabditis elegans):CELE_C30F8.2 vha-16

Monarch:172134 vha-16

NCBI Gene:172134 vha-16

UCSC:Q95YD5 vha-16

Wormbase:WBGene00016258

Reference Transcript

RefSeq:NM_059114.4 vha-16

Other Identifiers

172134

177070_s_at

18465772

A_12_P104551

A_12_P140185

A_12_P140186

C30F8.2

C30F8.2_766-825_0.948_3_B

C30F8.2_838-897_0.949_2_A

C30F8.2_903-962_0.945_4_C

C30F8_2P00020

C30F8_2P00427

C30F8_2P00977

CE29684

CE_WBGene00016258_A

CGZ0006777

GO:0003674

GO:0005575

GO:0005622

GO:0005737

GO:0005764

GO:0005765

GO:0005768

GO:0005769

GO:0005773

GO:0005886

GO:0006810

GO:0006811

GO:0007034

GO:0007035

GO:0008150

GO:0008553

GO:0015078

GO:0016471

GO:0022857

GO:0031410

GO:0032991

GO:0033179

GO:0033181

GO:0042592

GO:0043226

GO:0046961

GO:0055085

GO:1902600

WBGene00016258

cea2.c.00939

Participant Of

hasComponent

ATP6V0 [lysosomal membrane]

Other forms of this molecule

vha-16 [lysosomal membrane]

vha-16 [phagocytic vesicle membrane]

vha-16 [endosome membrane]

Inferred From

ATP6V0D1 [lysosomal membrane] (Homo sapiens)

ATP6V0D [lysosomal membrane] (Homo sapiens)

Cross References

RefSeq

NP_491515.2

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