Reactome | flr-2 [extracellular region]

flr-2 [extracellular region]

Stable Identifier

R-CEL-8942422

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

extracellular region

Synonyms

GPHA2, Q21013

Locations in the PathwayBrowser

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Signal Transduction (Caenorhabditis elegans)

- Signaling by GPCR (Caenorhabditis elegans)
  - GPCR downstream signalling (Caenorhabditis elegans)
    - G alpha (s) signalling events (Caenorhabditis elegans)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Caenorhabditis elegans)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Caenorhabditis elegans)
        
        TSHR:Thyrotropin [plasma membrane] (Caenorhabditis elegans)
        
        Thyrostimulin [extracellular region] (Caenorhabditis elegans)
        
        flr-2 [extracellular region] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Caenorhabditis elegans)
        
        TSHR:Thyrotropin [plasma membrane] (Caenorhabditis elegans)
        
        Thyrostimulin [extracellular region] (Caenorhabditis elegans)
        
        flr-2 [extracellular region] (Caenorhabditis elegans)
  - GPCR ligand binding (Caenorhabditis elegans)
    - Class A/1 (Rhodopsin-like receptors) (Caenorhabditis elegans)
      - Hormone ligand-binding receptors (Caenorhabditis elegans)
        
        Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin (Caenorhabditis elegans)
        
        TSHR:Thyrotropin [plasma membrane] (Caenorhabditis elegans)
        
        Thyrostimulin [extracellular region] (Caenorhabditis elegans)
        
        flr-2 [extracellular region] (Caenorhabditis elegans)
        
        Thyrostimulin [extracellular region] (Caenorhabditis elegans)
        
        flr-2 [extracellular region] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q21013

Gene Names

flr-2

Reference Genes

BioGPS Gene:186548 flr-2

ENSEMBL:WBGene00001466

KEGG Gene (Caenorhabditis elegans):CELE_F58H1.4 flr-2

Monarch:186548 flr-2

NCBI Gene:186548 flr-2

UCSC:Q21013 flr-2

Wormbase:WBGene00001466

Reference Transcript

RefSeq:NM_073597.2 flr-2

Other Identifiers

179441_at

18591845

186548

A_12_P108502

CE_WBGene00010287_A

CGZ0025395

F58H1.4

F58H1.4_126-185_0.825_12_C

F58H1.4_264-323_0.930_1_A

F58H1.4_37-96_0.918_2_B

F58H1_4P00041

F58H1_4P00052

GO:0003674

GO:0005575

GO:0005576

GO:0005615

GO:0007165

GO:0007166

GO:0008150

GO:0051427

WBGene00010287

Participant Of

hasComponent

Thyrostimulin [extracellular region]

Inferred From

GPHA2 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_505998.2

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