Reactome | MyrG-SRC [plasma membrane]

MyrG-SRC [plasma membrane]

Stable Identifier

R-CEL-8876922

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

plasma membrane

Synonyms

G5EE56

Locations in the PathwayBrowser

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Hemostasis (Caenorhabditis elegans)

- Platelet activation, signaling and aggregation (Caenorhabditis elegans)
  - Platelet Aggregation (Plug Formation) (Caenorhabditis elegans)
    - Integrin signaling (Caenorhabditis elegans)
      - Autophosphorylation of SRC (Caenorhabditis elegans)
        
        Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Caenorhabditis elegans)
        
        Integrin alphaIIb beta3:SRC [plasma membrane] (Caenorhabditis elegans)
        
        MyrG-SRC [plasma membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5EE56

Reference Genes

BioGPS Gene:171722

ENSEMBL:WBGene00005077

KEGG:cel:CELE_Y92H12A.1

Monarch:171722

NCBI Gene:171722

UCSC:G5EE56

Wormbase:WBGene00005077

Reference Transcript

Other Identifiers

171722

176215_at

176306_at

18463566

A_12_P116399

A_12_P145805

CE31390

CE_WBGene00005077_A

CE_WBGene00005077_B

CGZ0055280

GO:0000132

GO:0001714

GO:0001891

GO:0002376

GO:0003824

GO:0004672

GO:0004713

GO:0004715

GO:0005102

GO:0005515

GO:0005524

GO:0005886

GO:0006468

GO:0007010

GO:0007169

GO:0008595

GO:0009792

GO:0016740

GO:0022414

GO:0030154

GO:0035262

GO:0038007

GO:0040017

GO:0040019

GO:0042995

GO:0043226

GO:0043292

GO:0045087

GO:0046872

GO:0048557

GO:0048856

GO:0050731

GO:0070986

GO:0071679

GO:0098542

GO:0140096

GO:1990890

WBGene00005077

Y92H12A.1

Y92H12A.1_1101-1160_0.923_4_C

Y92H12A.1_1338-1397_0.928_2_B

Y92H12A.1_1461-1520_0.946_1_A

Y92H12A_1P00250

Y92H12A_1P00689

Y92H12A_1P00967

Participates

as a component of

as an input of

SH2 domain of Src binds to the active receptor (Caenorhabditis elegans)

Other forms of this molecule

SRC-2 [cytosol]

phospho-MyrG-p-Y419-SRC [plasma membrane]

FYN [cytosol]

LCK [cytosol]

SRC-1 [plasma membrane]

phospho-MyrG-p-Y426-YES1 [plasma membrane]

phospho-MyrG-p-Y420-FYN-1 [plasma membrane]

phospho-MyrG,p-Y530-SRC [plasma membrane]

phospho-p-Y420-FYN [cytosol]

LYN [cytosol]

phospho-p-Y419-SRC [cytosol]

FGR [cytosol]

YES1 [cytosol]

HCK [cytosol]

phospho-p-Y397-LYN [plasma membrane]

LYN [plasma membrane]

phospho-p-Y394-LCK [plasma membrane]

phospho-p-Y419-SRC-1 [plasma membrane]

phospho-p-S21,Y420-FYN [cytosol]

FGR [secretory granule lumen]

FGR [extracellular region]

SRC [cytosol]

phospho-p-Y419-SRC [cytosol]

Inferred From

MyrG-SRC [plasma membrane] (Homo sapiens)

Modified Residues

Name

N-myristoylglycine at 2 (in Homo sapiens)

Coordinate

PsiMod Name

N-myristoylglycine [MOD:00068]

PsiMod Definition

A protein modification that effectively converts a glycine residue to N-myristoylglycine.

Cross References

RefSeq

NP_490866.4, NP_001293421.1, NP_001293422.1, NP_001293420.1

ENSEMBL

WBGene00005077, Y92H12A.1a.1, Y92H12A.1a.1

PRO

G5EE56

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q09442	1	sap-49 [nucleoplasm] (R-CEL-71975)	0.553	3
UniProt:Q9BIF4	4	ehs-1 [cytosol] (R-CEL-8935900) ehs-1 [cytosol] (R-CEL-182920) phospho-ehs-1 [cytosol] (R-CEL-8867028) ehs-1 [plasma membrane] (R-CEL-182937)	0.553	3