Reactome | snpc-1.1 [nucleoplasm]

snpc-1.1 [nucleoplasm]

Stable Identifier

R-CEL-83726

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

SNAPC1, Q17694

Locations in the PathwayBrowser

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Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - RNA polymerase II transcribes snRNA genes (Caenorhabditis elegans)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc [nucleoplasm] (Caenorhabditis elegans)
        
        snpc-1.1 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc [nucleoplasm] (Caenorhabditis elegans)
        
        snpc-1.1 [nucleoplasm] (Caenorhabditis elegans)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc [nucleoplasm] (Caenorhabditis elegans)
        
        snpc-1.1 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc [nucleoplasm] (Caenorhabditis elegans)
        
        snpc-1.1 [nucleoplasm] (Caenorhabditis elegans)
    - Integrator complex processes the 3' end of snRNA (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc [nucleoplasm] (Caenorhabditis elegans)
        
        snpc-1.1 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc [nucleoplasm] (Caenorhabditis elegans)
        
        snpc-1.1 [nucleoplasm] (Caenorhabditis elegans)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc [nucleoplasm] (Caenorhabditis elegans)
        
        snpc-1.1 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc [nucleoplasm] (Caenorhabditis elegans)
        
        snpc-1.1 [nucleoplasm] (Caenorhabditis elegans)
    - RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Caenorhabditis elegans)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc [nucleoplasm] (Caenorhabditis elegans)
        
        snpc-1.1 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        SNAPc [nucleoplasm] (Caenorhabditis elegans)
        
        snpc-1.1 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q17694

Gene Names

snpc-1.1

Reference Genes

BioGPS Gene:174255 snpc-1.1

CTD Gene:174255 snpc-1.1

ENSEMBL:WBGene00015513

Monarch:174255 snpc-1.1

NCBI Gene:174255 snpc-1.1

UCSC:Q17694 snpc-1.1

Wormbase:WBGene00015513

Reference Transcript

RefSeq:NM_063235.5 snpc-1.1

Other Identifiers

174255

180127_at

18493582

A_12_P110892

C06A8.2

C06A8.2_1327-1386_0.969_1_A

C06A8.2_468-527_0.843_31_C

C06A8.2_886-945_0.882_20_B

C06A8_2P00156

C06A8_2P00731

C06A8_2P01311

CE31292

CE_WBGene00015513_A

CE_WBGene00015513_C

CGZ0002777

WBGene00015513

cea2.p.29326

Participates

as a component of

SNAPc [nucleoplasm] (Caenorhabditis elegans)

Inferred From

SNAPC1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_495636.2

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