Reactome | rps-5 [cytosol]

rps-5 [cytosol]

Stable Identifier

R-CEL-72379

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

RPS5, P49041

Locations in the PathwayBrowser

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Metabolism of RNA (Caenorhabditis elegans)

- Nonsense-Mediated Decay (NMD) (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Caenorhabditis elegans)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-5 [cytosol] (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-5 [cytosol] (Caenorhabditis elegans)
    - SMG6 hydrolyzes mRNA with premature termination codon (Caenorhabditis elegans)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-5 [cytosol] (Caenorhabditis elegans)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-5 [cytosol] (Caenorhabditis elegans)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-5 [cytosol] (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Caenorhabditis elegans)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-5 [cytosol] (Caenorhabditis elegans)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-5 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:P49041

Gene Names

rps-5

Reference Genes

BioGPS Gene:178012 rps-5

CTD Gene:178012 rps-5

ENSEMBL:WBGene00004474

Monarch:178012 rps-5

NCBI Gene:178012 rps-5

UCSC:P49041 rps-5

Wormbase:WBGene00004474

Reference Transcript

RefSeq:NM_069676.3 rps-5

Other Identifiers

174085_s_at

178012

18555772

191618_s_at

A_12_P101586

A_12_P155225

CE06360

CE_WBGene00004474_A

CGZ0033401

GO:0003723

GO:0003735

GO:0005198

GO:0005840

GO:0006412

GO:0015935

GO:0043226

T05E11.1

T05E11.1_266-325_0.933_3_B

T05E11.1_547-606_0.891_12_C

T05E11.1_583-642_0.946_1_A

T05E11_1P00071

T05E11_1P00384

T05E11_1P00445

WBGene00004474

cea2.c.30783

Participates

as a component of

40S ribosomal complex [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

rps-5 [nucleoplasm]

Inferred From

RPS5 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_502077.1

PRO

P49041

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