Reactome | ints-2 [nucleoplasm]

ints-2 [nucleoplasm]

Stable Identifier

R-CEL-6807448

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

INTS2, E5QCH1

Locations in the PathwayBrowser

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Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - RNA polymerase II transcribes snRNA genes (Caenorhabditis elegans)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-2 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-2 [nucleoplasm] (Caenorhabditis elegans)
    - Integrator complex processes the 3' end of snRNA (Caenorhabditis elegans)
      - Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-2 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-2 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-2 [nucleoplasm] (Caenorhabditis elegans)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-2 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-2 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:E5QCH1

Gene Names

ints-2

Reference Genes

BioGPS Gene:179921 ints-2

ENSEMBL:WBGene00013877

Monarch:179921 ints-2

NCBI Gene:179921 ints-2

Wormbase:WBGene00013877

Reference Transcript

RefSeq:NM_001269640.1 ints-2

Other Identifiers

177852_at

179921

18580764

A_12_P104282

CE15203

CE_WBGene00013877_A

CE_WBGene00013877_B

CE_WBGene00013877_C

CGZ0055778

GO:0005634

GO:0032039

GO:0043226

WBGene00013877

ZC376.6

ZC376.6_2653-2712_0.882_30_B

ZC376.6_2838-2897_0.912_14_A

ZC376.6_3412-3471_0.945_1_C

ZC376_6P02092

ZC376_6P02787

cea2.p.130944

Participates

as a component of

Integrator [nucleoplasm] (Caenorhabditis elegans)

Inferred From

INTS2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001256569.1