Reactome | pkd-2 [Golgi-associated vesicle membrane]

pkd-2 [Golgi-associated vesicle membrane]

Stable Identifier

R-CEL-5623411

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

Golgi-associated vesicle membrane

Synonyms

PKD2, Q9U1S7

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Caenorhabditis elegans)

- Cilium Assembly (Caenorhabditis elegans)
  - Cargo trafficking to the periciliary membrane (Caenorhabditis elegans)
    - VxPx cargo-targeting to cilium (Caenorhabditis elegans)
      - Cargo-carrying vesicles bud from the TGN (Caenorhabditis elegans)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        pkd-2 [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
      - The exocyst complex binds to RAB3IP in the ciliary targeting complex (Caenorhabditis elegans)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        pkd-2 [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        pkd-2 [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
      - VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Caenorhabditis elegans)
        
        exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)
        
        pkd-2 [Golgi-associated vesicle membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q9U1S7

Gene Names

pkd-2

Reference Genes

BioGPS Gene:178424 pkd-2

ENSEMBL:WBGene00004035

Monarch:178424 pkd-2

NCBI Gene:178424 pkd-2

UCSC:Q9U1S7 pkd-2

Wormbase:WBGene00004035

Reference Transcript

RefSeq:NM_070437.4 pkd-2

Other Identifiers

178424

18560282

188076_s_at

A_12_P105580

CE32549

CE_WBGene00004035_A

CGZ0053516

GO:0005509

GO:0016020

WBGene00004035

Y73F8A.1

Y73F8A.1_1194-1253_0.886_21_C

Y73F8A.1_1585-1644_0.921_7_A

Y73F8A.1_1748-1807_0.913_9_B

Y73F8A_1P00760

Y73F8A_1P01409

Y73F8A_1P02051

cea2.p.104419

Participates

as a candidate of

VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Caenorhabditis elegans)

Other forms of this molecule

pkd-2 [ciliary membrane]

pkd-2 [Golgi membrane]

Inferred From

PKD2 [Golgi-associated vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_502838.3

PRO

Q9U1S7