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FN1(32-2477) [extracellular region]
Stable Identifier
R-CEL-54851
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
extracellular region
Synonyms
Q18096
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to mechanical stimuli (Caenorhabditis elegans)
Response of endothelial cells to shear stress (Caenorhabditis elegans)
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Caenorhabditis elegans)
PP2A dephosphorylates serine-127 of YAP1 (Caenorhabditis elegans)
p-S26-ANXA2:PP2A:p-S715-PDE4D5:ITGA5:ITGB1:fibronectin [plasma membrane] (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Phosphorylation of ABL1 on tyrosine-393 in response to oscillatory shear stress (Caenorhabditis elegans)
p-S26-ANXA2:ITGA5:ITGB1:Ca2+:fibronectin [plasma membrane] (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow (Caenorhabditis elegans)
p-S26-ANXA2:ITGA5:ITGB1:Ca2+:fibronectin [plasma membrane] (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Extracellular matrix organization (Caenorhabditis elegans)
Degradation of the extracellular matrix (Caenorhabditis elegans)
Fibronectin degradation by ADAM8 (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Fibronectin degradation by MMP14 (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
ECM proteoglycans (Caenorhabditis elegans)
Tenascins C, R, (X, N) bind fibronectin matrix (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Tenascins C, R, (X, N):Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Elastic fibre formation (Caenorhabditis elegans)
Molecules associated with elastic fibres (Caenorhabditis elegans)
Fibulin-1 and -2 bind fibronectin (Caenorhabditis elegans)
FBLN1, FBLN2:Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Fibronectin matrix formation (Caenorhabditis elegans)
FN1 aggregation (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Integrin alpha5beta1:FN1 dimer [plasma membrane] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Integrin alpha5beta1:Fibronectin matrix [plasma membrane] (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
FN1 binds Collagen types I-V, VII (Caenorhabditis elegans)
FN1(32-2386):Collagen types I-V, VII [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
FN1 dimerizes (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Integrin alpha5beta1 binds FN1 dimer (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Integrin alpha5beta1:FN1 dimer [plasma membrane] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Integrin cell surface interactions (Caenorhabditis elegans)
Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Integrin alpha4beta1, alpha8beta1, alphaVbeta6:Fibronectin matrix [plasma membrane] (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Interaction of integrin alphaIIbbeta3 with Fibronectin (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Integrin alpha2bbeta3:FN1(32-2386) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Non-integrin membrane-ECM interactions (Caenorhabditis elegans)
HSPG2 binds FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer (Caenorhabditis elegans)
FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
HSPG2:FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] (Caenorhabditis elegans)
FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Syndecan interactions (Caenorhabditis elegans)
Syndecan-1 binds fibronectin (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Syndecan-1:Fibronectin matrix [plasma membrane] (Caenorhabditis elegans)
Fibronectin matrix [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Hemostasis (Caenorhabditis elegans)
Cell surface interactions at the vascular wall (Caenorhabditis elegans)
Integrin alpha5beta1 binds FN1 dimer (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Integrin alpha5beta1:FN1 dimer [plasma membrane] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Platelet activation, signaling and aggregation (Caenorhabditis elegans)
Platelet Aggregation (Plug Formation) (Caenorhabditis elegans)
Integrin signaling (Caenorhabditis elegans)
Autophosphorylation of PTK2 at Y397 (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Autophosphorylation of SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Clustering of Integrin alphaIIb beta3 complexes (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
GRB2:SOS provides linkage to MAPK signaling for Integrins (Caenorhabditis elegans)
Interaction of SOS with GRB2 bound to FADK1 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Recruitment of GRB2 to p-PTK2 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Interaction of integrin alphaIIb beta3 with Fibrinogen (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Phosphorylation of pPTK2 by SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Release of CSK from SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
SYK activation by SRC (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
SYK binds to integrin alphaIIb beta3 (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Translocation of PTK2 to Focal complexes (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Response to elevated platelet cytosolic Ca2+ (Caenorhabditis elegans)
Platelet degranulation (Caenorhabditis elegans)
Exocytosis of platelet alpha granule contents (Caenorhabditis elegans)
Platelet alpha granule contents [extracellular region] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Integrin signaling (Caenorhabditis elegans)
Autophosphorylation of PTK2 at Y397 (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Autophosphorylation of SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Clustering of Integrin alphaIIb beta3 complexes (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
GRB2:SOS provides linkage to MAPK signaling for Integrins (Caenorhabditis elegans)
Interaction of SOS with GRB2 bound to FADK1 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Recruitment of GRB2 to p-PTK2 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Interaction of integrin alphaIIb beta3 with Fibrinogen (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Phosphorylation of pPTK2 by SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Release of CSK from SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
SYK activation by SRC (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
SYK binds to integrin alphaIIb beta3 (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Translocation of PTK2 to Focal complexes (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
MAPK family signaling cascades (Caenorhabditis elegans)
MAPK1/MAPK3 signaling (Caenorhabditis elegans)
RAF/MAP kinase cascade (Caenorhabditis elegans)
MAP2K and MAPK activation (Caenorhabditis elegans)
Dissociation of RAS:RAF complex (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Dual mechanism MAPK inhibitors bind MAPKs (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
MAP2Ks and MAPKs bind to the activated RAF complex (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
MAP2Ks phosphorylate MAPKs (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
RAF phosphorylates MAP2K dimer (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
FN1(32-2477) [extracellular region] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:Q18096
Reference Genes
BioGPS Gene:174432
CTD Gene:174432
ENSEMBL:WBGene00007687
Monarch:174432
NCBI Gene:174432
UCSC:Q18096
Wormbase:WBGene00007687
Wormbase:WBGene00007687
Reference Transcript
RefSeq:NM_001361871.2
Other Identifiers
174432
GO:0005515
Participates
as a component of
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
FN1(32-2386):Collagen types I-V, VII [extracellular region] (Caenorhabditis elegans)
FN1 dimer [extracellular region] (Caenorhabditis elegans)
Integrin alpha2bbeta3:FN1(32-2386) [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
as an input of
Interaction of integrin alphaIIb beta3 with Fibrinogen (Caenorhabditis elegans)
FN1 binds Collagen types I-V, VII (Caenorhabditis elegans)
FN1 aggregation (Caenorhabditis elegans)
FN1 dimerizes (Caenorhabditis elegans)
Interaction of integrin alphaIIbbeta3 with Fibronectin (Caenorhabditis elegans)
as a member of
Platelet alpha granule contents [extracellular region] (Caenorhabditis elegans)
Other forms of this molecule
TNXB [extracellular region]
FN1(32-271) [extracellular region]
FN1(272-2477) [extracellular region]
FN1(32-?) [extracellular region]
FN1(?-2386) [extracellular region]
phospho-p-FN1 [endoplasmic reticulum lumen]
phospho-p-TNC [endoplasmic reticulum lumen]
TNC [endoplasmic reticulum lumen]
FN1 [endoplasmic reticulum lumen]
TNC [extracellular region]
FN1(32-2477) [platelet alpha granule lumen]
Inferred From
Integrin alphaIIb beta3 ECM ligands [extracellular region]
(Homo sapiens)
FN1(32-2477) [extracellular region]
(Homo sapiens)
Cross References
RefSeq
NP_001348641.1
ENSEMBL
C18E9.7.1
,
C18E9.7.1
,
WBGene00007687
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