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SLC38A9 [lysosomal membrane]
Stable Identifier
R-CEL-5215938
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
lysosomal membrane
Synonyms
Q19425
Locations in the PathwayBrowser
Expand all
Autophagy (Caenorhabditis elegans)
Macroautophagy (Caenorhabditis elegans)
Active MTORC1 binds the ULK1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Active MTORC1 phosphorylates ULK1 (Caenorhabditis elegans)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
MTORC1 dissociates from ULK complex (Caenorhabditis elegans)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Rheb in the MTORC1 complex hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Caenorhabditis elegans)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to starvation (Caenorhabditis elegans)
Amino acids regulate mTORC1 (Caenorhabditis elegans)
RRAGA,B exchanges GDP for GTP (Caenorhabditis elegans)
SLC38A9:L-Arg [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9:L-Arg [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9:L-Arg [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Caenorhabditis elegans)
SLC38A9:L-Arg [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9:L-Arg [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Caenorhabditis elegans)
SLC38A9:L-Arg [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9:L-Arg [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional Regulation by TP53 (Caenorhabditis elegans)
TP53 Regulates Metabolic Genes (Caenorhabditis elegans)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Intracellular signaling by second messengers (Caenorhabditis elegans)
PIP3 activates AKT signaling (Caenorhabditis elegans)
PTEN Regulation (Caenorhabditis elegans)
Regulation of PTEN gene transcription (Caenorhabditis elegans)
MAF1 translocates to the nucleus (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 phosphorylates MAF1 (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
MTOR signalling (Caenorhabditis elegans)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Caenorhabditis elegans)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Energy dependent regulation of mTOR by LKB1-AMPK (Caenorhabditis elegans)
AMPK phosphorylates Raptor in the mTORC1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Formation of active mTORC1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 phosphorylates AKT1S1 (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1-mediated signalling (Caenorhabditis elegans)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:Q19425
Reference Genes
BioGPS Gene:177997
ENSEMBL:WBGene00008774
KEGG:cel:CELE_F13H10.3
Monarch:177997
NCBI Gene:177997
UCSC:Q19425
Wormbase:WBGene00008774
Wormbase:WBGene00008774
Reference Transcript
RefSeq:NM_171417.8
Other Identifiers
177997
GO:0003333
GO:0005764
GO:0005765
GO:0005768
GO:0006865
GO:0015179
GO:0016020
GO:0031902
GO:0046872
GO:0055085
GO:1902475
Participates
as a component of
SLC38A9:L-Arg [lysosomal membrane] (Caenorhabditis elegans)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
Inferred From
SLC38A9 [lysosomal membrane]
(Homo sapiens)
Cross References
RefSeq
NP_741486.1
ENSEMBL
F13H10.3a.1
,
F13H10.3a.1
,
WBGene00008774
PRO
Q19425
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