Reactome | gbb-2 [plasma membrane]

gbb-2 [plasma membrane]

Stable Identifier

R-CEL-420747

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

plasma membrane

Synonyms

GABBR2, G5ECB2

Locations in the PathwayBrowser

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Signal Transduction (Caenorhabditis elegans)

- Signaling by GPCR (Caenorhabditis elegans)
  - GPCR downstream signalling (Caenorhabditis elegans)
    - G alpha (i) signalling events (Caenorhabditis elegans)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        GABBR1:GABBR2:GABA [plasma membrane] (Caenorhabditis elegans)
        
        GABBR1:GABBR2 [plasma membrane] (Caenorhabditis elegans)
        
        gbb-2 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        GABBR1:GABBR2:GABA [plasma membrane] (Caenorhabditis elegans)
        
        GABBR1:GABBR2 [plasma membrane] (Caenorhabditis elegans)
        
        gbb-2 [plasma membrane] (Caenorhabditis elegans)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        GABBR1:GABBR2:GABA [plasma membrane] (Caenorhabditis elegans)
        
        GABBR1:GABBR2 [plasma membrane] (Caenorhabditis elegans)
        
        gbb-2 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        GABBR1:GABBR2:GABA [plasma membrane] (Caenorhabditis elegans)
        
        GABBR1:GABBR2 [plasma membrane] (Caenorhabditis elegans)
        
        gbb-2 [plasma membrane] (Caenorhabditis elegans)
      - The Ligand:GPCR:Gi complex dissociates (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        GABBR1:GABBR2:GABA [plasma membrane] (Caenorhabditis elegans)
        
        GABBR1:GABBR2 [plasma membrane] (Caenorhabditis elegans)
        
        gbb-2 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        GABBR1:GABBR2:GABA [plasma membrane] (Caenorhabditis elegans)
        
        GABBR1:GABBR2 [plasma membrane] (Caenorhabditis elegans)
        
        gbb-2 [plasma membrane] (Caenorhabditis elegans)
  - GPCR ligand binding (Caenorhabditis elegans)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Caenorhabditis elegans)
      - GABAB heterodimeric receptor binds GABA (Caenorhabditis elegans)
        
        GABBR1:GABBR2 [plasma membrane] (Caenorhabditis elegans)
        
        gbb-2 [plasma membrane] (Caenorhabditis elegans)
        
        GABBR1:GABBR2:GABA [plasma membrane] (Caenorhabditis elegans)
        
        GABBR1:GABBR2 [plasma membrane] (Caenorhabditis elegans)
        
        gbb-2 [plasma membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5ECB2

Gene Names

gbb-2

Reference Genes

BioGPS Gene:191240 gbb-2

ENSEMBL:WBGene00022675

Monarch:191240 gbb-2

NCBI Gene:191240 gbb-2

Wormbase:WBGene00022675

Reference Transcript

RefSeq:NM_068178.3 gbb-2

Other Identifiers

183035_at

183308_at

18560792

191240

A_12_P136216

A_12_P136217

A_12_P136690

A_12_P136691

A_12_P136692

A_12_P136770

A_12_P136771

A_12_P136772

A_12_P136773

A_12_P136774

CE07619

CE07620

CGZ0056482

GO:0004930

GO:0004965

GO:0007186

GO:0016020

GO:0023052

GO:0060089

WBGene00022675

WBGene00022676

ZK180.1

ZK180.1_1594-1653_0.875_11_C

ZK180.1_1692-1751_0.879_9_B

ZK180.1_1831-1890_0.900_6_A

ZK180.2

ZK180_1P00100

ZK180_1P00740

ZK180_2P00288

ZK180_2P00530

cea2.i.31616

Participates

as a component of

GABBR1:GABBR2 [plasma membrane] (Caenorhabditis elegans)

Inferred From

GABBR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_500579.3

PRO

G5ECB2

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