Reactome | dop-2 [plasma membrane]

dop-2 [plasma membrane]

Stable Identifier

R-CEL-391007

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

plasma membrane

Synonyms

HTR5A, E7EM37

Locations in the PathwayBrowser

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Signal Transduction (Caenorhabditis elegans)

- Signaling by GPCR (Caenorhabditis elegans)
  - GPCR downstream signalling (Caenorhabditis elegans)
    - G alpha (i) signalling events (Caenorhabditis elegans)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        dop-2 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        dop-2 [plasma membrane] (Caenorhabditis elegans)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        dop-2 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        dop-2 [plasma membrane] (Caenorhabditis elegans)
      - The Ligand:GPCR:Gi complex dissociates (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        dop-2 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        dop-2 [plasma membrane] (Caenorhabditis elegans)
  - GPCR ligand binding (Caenorhabditis elegans)
    - Class A/1 (Rhodopsin-like receptors) (Caenorhabditis elegans)
      - Amine ligand-binding receptors (Caenorhabditis elegans)
        
        Serotonin receptors (Caenorhabditis elegans)
        
        HTR1 and 5A receptors can bind serotonin (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        dop-2 [plasma membrane] (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Caenorhabditis elegans)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HTR5A [plasma membrane] (Caenorhabditis elegans)
        
        dop-2 [plasma membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:E7EM37

Gene Names

dop-2

Reference Genes

BioGPS Gene:179347 dop-2

CTD Gene:179347 dop-2

ENSEMBL:WBGene00001053

Monarch:179347 dop-2

NCBI Gene:179347 dop-2

Wormbase:WBGene00001053

Reference Transcript

Other Identifiers

179347

18573104

190437_at

A_12_P106321

CE31360

CE_WBGene00001053_A

CE_WBGene00001053_B

CGZ0028892

CGZ0028893

GO:0004930

GO:0007186

GO:0016020

GO:0023052

GO:0060089

K09G1.4

K09G1.4b_177-236_0.788_68_B

K09G1.4b_317-376_0.796_63_A

K09G1.4b_544-603_0.667_177_C

K09G1_4aP00706

K09G1_4aP01335

K09G1_4aP02058

K09G1_4bP01023

K09G1_4bP01029

K09G1_4bP01073

WBGene00001053

cea2.p.120966

Participates

as a member of

Homologues of HTR5A [plasma membrane] (Caenorhabditis elegans)

Other forms of this molecule

dop-2 [plasma membrane]

Inferred From

HTR5A [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001256126.1, NP_001256127.1, NP_001024048.1, NP_001024047.1

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