Reactome | par-2 [nucleoplasm]

par-2 [nucleoplasm]

Stable Identifier

R-CEL-349454

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

RFWD2, Q965F9

Locations in the PathwayBrowser

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Cell Cycle (Caenorhabditis elegans)

- Cell Cycle Checkpoints (Caenorhabditis elegans)
  - G1/S DNA Damage Checkpoints (Caenorhabditis elegans)
    - p53-Dependent G1/S DNA damage checkpoint (Caenorhabditis elegans)
      - p53-Dependent G1 DNA Damage Response (Caenorhabditis elegans)
        
        Stabilization of p53 (Caenorhabditis elegans)
        
        Autodegradation of the E3 ubiquitin ligase COP1 (Caenorhabditis elegans)
        
        Phosphorylation of COP1 at Ser-387 by ATM (Caenorhabditis elegans)
        
        par-2 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q965F9

Gene Names

par-2

Reference Genes

BioGPS Gene:175275 par-2

CTD Gene:175275 par-2

ENSEMBL:WBGene00003917

KEGG Gene (Caenorhabditis elegans):CELE_F58B6.3 par-2

Monarch:175275 par-2

NCBI Gene:175275 par-2

UCSC:Q965F9 par-2

Wormbase:WBGene00003917

Reference Transcript

RefSeq:NM_001027459.4 par-2

Other Identifiers

172125_x_at

175275

175620_at

18512928

A_12_P109537

CE_WBGene00003917_A

CE_WBGene00003917_B

CGZ0025173

F58B6.3

F58B6.3b

F58B6.3b_1017-1076_0.885_16_B

F58B6.3b_1467-1526_0.948_6_A

F58B6.3b_882-941_0.862_21_C

F58B6_3bP01071

F58B6_3bP01262

F58B6_3bP01516

GO:0000132

GO:0000209

GO:0000278

GO:0003674

GO:0005515

GO:0005546

GO:0005547

GO:0005575

GO:0005622

GO:0005737

GO:0005938

GO:0006464

GO:0007010

GO:0007049

GO:0008017

GO:0008092

GO:0008150

GO:0008289

GO:0008356

GO:0019899

GO:0019901

GO:0030010

GO:0030154

GO:0032991

GO:0043167

GO:0043186

GO:0043226

GO:0045167

GO:0051301

GO:0061630

GO:0061803

WBGene00003917

cea2.p.66791

Participates

as a member of

DCAF protein [nucleoplasm] (Caenorhabditis elegans)

as an input of

Phosphorylation of COP1 at Ser-387 by ATM (Caenorhabditis elegans)

Other forms of this molecule

phospho-par-2 [cytosol]

phospho-par-2 [nucleoplasm]

Inferred From

RFWD2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001022630.2

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P34269	3	tyr-1 [melanosome membrane] (R-CEL-8878574-3) tyr-1 [melanosome membrane] (R-CEL-5662685-3) tyr-1 [melanosome membrane] (R-CEL-5617243)	0.508	2