Reactome | efn-2 [plasma membrane]

efn-2 [plasma membrane]

Stable Identifier

R-CEL-2682339-4

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

plasma membrane

Synonyms

EFNA1, Q9U3M2

Locations in the PathwayBrowser

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Developmental Biology (Caenorhabditis elegans)

- Nervous system development (Caenorhabditis elegans)
  - Axon guidance (Caenorhabditis elegans)
    - EPH-Ephrin signaling (Caenorhabditis elegans)
      - EPH receptors autophosphorylate (Caenorhabditis elegans)
        
        EPH-ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
      - EPH-ephrin mediated repulsion of cells (Caenorhabditis elegans)
        
        EPHA binds TIAM1 (Caenorhabditis elegans)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
        
        SFKs phosphorylate VAV2,3 (Caenorhabditis elegans)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
        
        TIAM1 exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
        
        EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
        
        VAV exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHs bind VAV2,3 (Caenorhabditis elegans)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
      - EPH:EFN dimers tetramerise (Caenorhabditis elegans)
        
        EPH-EFN dimers [plasma membrane] (Caenorhabditis elegans)
        
        EPHA:EFNA dimers [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
      - EPH:EFN tetramers oligomerise (Caenorhabditis elegans)
        
        EPH-EFN dimers [plasma membrane] (Caenorhabditis elegans)
        
        EPHA:EFNA dimers [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
        
        EPH-ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
      - EPHA-mediated growth cone collapse (Caenorhabditis elegans)
        
        NGEF exchanges GTP for GDP on RHOA (Caenorhabditis elegans)
        
        EFNAs:p-EPHAs:SFKs:p-Y179-NGEF [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
      - EPHAs bind EFNAs (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-2 [plasma membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q9U3M2

Gene Names

efn-2

Reference Genes

BioGPS Gene:177949 efn-2

ENSEMBL:WBGene00001163

KEGG Gene (Caenorhabditis elegans):CELE_C43F9.8 efn-2

Monarch:177949 efn-2

NCBI Gene:177949 efn-2

UCSC:Q9U3M2 efn-2

Wormbase:WBGene00001163

Reference Transcript

RefSeq:NM_069554.5 efn-2

Other Identifiers

177949

178996_at

18535078

A_12_P101058

C43F9.8

C43F9.8_112-171_0.916_3_B

C43F9.8_215-274_0.916_2_A

C43F9.8_515-574_0.920_1_C

C43F9_8P00125

C43F9_8P00288

C43F9_8P00522

CE23593

CE_WBGene00001163_A

CE_WBGene00001163_B

CGZ0008696

GO:0016020

WBGene00001163

cea2.p.87942

Participates

as a member of

Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)

Other forms of this molecule

phospho-efn-2 [plasma membrane]

efn-2 [plasma membrane]

Inferred From

EFNA1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_501955.2

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