Reactome | gex-3 [cytosol]

gex-3 [cytosol]

Stable Identifier

R-CEL-200979

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

NCKAP1, P55163

Locations in the PathwayBrowser

Expand all

Immune System (Caenorhabditis elegans)

- Innate Immune System (Caenorhabditis elegans)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Caenorhabditis elegans)
    - Regulation of actin dynamics for phagocytic cup formation (Caenorhabditis elegans)
      - (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Caenorhabditis elegans)
        
        Mother filament:branching complex [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
        
        p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
        
        p-Y,S,T-WRC [cytosol] (Caenorhabditis elegans)
        
        gex-3 [cytosol] (Caenorhabditis elegans)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
        
        p-Y-WRC [cytosol] (Caenorhabditis elegans)
        
        gex-3 [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
        
        p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
        
        p-Y,S,T-WRC [cytosol] (Caenorhabditis elegans)
        
        gex-3 [cytosol] (Caenorhabditis elegans)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
        
        p-Y-WRC [cytosol] (Caenorhabditis elegans)
        
        gex-3 [cytosol] (Caenorhabditis elegans)
      - ABL phosphorylates WAVEs (Caenorhabditis elegans)
        
        WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
        
        WAVE Regulatory Complex [cytosol] (Caenorhabditis elegans)
        
        gex-3 [cytosol] (Caenorhabditis elegans)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
        
        p-Y-WRC [cytosol] (Caenorhabditis elegans)
        
        gex-3 [cytosol] (Caenorhabditis elegans)
      - Detachment of WASP/WAVE (Caenorhabditis elegans)
        
        Mother filament:branching complex [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
        
        p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
        
        p-Y,S,T-WRC [cytosol] (Caenorhabditis elegans)
        
        gex-3 [cytosol] (Caenorhabditis elegans)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
        
        p-Y-WRC [cytosol] (Caenorhabditis elegans)
        
        gex-3 [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
        
        p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
        
        p-Y,S,T-WRC [cytosol] (Caenorhabditis elegans)
        
        gex-3 [cytosol] (Caenorhabditis elegans)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
        
        p-Y-WRC [cytosol] (Caenorhabditis elegans)
        
        gex-3 [cytosol] (Caenorhabditis elegans)
      - p-ERK phosphorylates WAVEs and ABI (Caenorhabditis elegans)
        
        p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Caenorhabditis elegans)
        
        p-Y,S,T-WRC [cytosol] (Caenorhabditis elegans)
        
        gex-3 [cytosol] (Caenorhabditis elegans)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Caenorhabditis elegans)
        
        p-Y-WRC [cytosol] (Caenorhabditis elegans)
        
        gex-3 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:P55163

Gene Names

gex-3

Reference Genes

BioGPS Gene:178191 gex-3

ENSEMBL:WBGene00001580

KEGG:cel:CELE_F28D1.10 gex-3

Monarch:178191 gex-3

NCBI Gene:178191 gex-3

UCSC:P55163 gex-3

Wormbase:WBGene00001580

Wormbase:WBGene00001580 gex-3

Reference Transcript

RefSeq:NM_069967.7 gex-3

Other Identifiers

178191

GO:0000902

GO:0005515

GO:0005737

GO:0007010

GO:0007015

GO:0010172

GO:0016477

GO:0018991

GO:0022414

GO:0030031

GO:0030054

GO:0030866

GO:0031209

GO:0048613

GO:0048668

GO:0048812

GO:0048870

GO:1901046

GO:1902474

GO:1903598

GO:2000370

Participates

as a candidate of

RAC3 effectors [cytosol] (Caenorhabditis elegans)

as a component of

Other forms of this molecule

gex-3 [secretory granule membrane]

gex-3 [plasma membrane]

gex-3 [ficolin-1-rich granule membrane]

gex-3 [cytosol]

Inferred From

NCKAP1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_502368.1

ENSEMBL

F28D1.10.1, F28D1.10.1, WBGene00001580

PRO

P55163

Cite Us!