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phospho-MyrG-p-Y419-SRC [plasma membrane]
Stable Identifier
R-CEL-1810408
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
plasma membrane
Synonyms
G5EE56
Locations in the PathwayBrowser
Expand all
Developmental Biology (Caenorhabditis elegans)
Nervous system development (Caenorhabditis elegans)
Axon guidance (Caenorhabditis elegans)
Netrin-1 signaling (Caenorhabditis elegans)
DCC mediated attractive signaling (Caenorhabditis elegans)
Activation of Cdc42 (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Activation of Rac1 (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
DCC interacting NCK-1 (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Phosphorylation of DCC by Fyn (Caenorhabditis elegans)
NTN1:DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Recruitment of Src and Fyn to DCC:FADK1 (Caenorhabditis elegans)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
NTN1:DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
RhoGTPase GEF's recruited to DCC (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Caenorhabditis elegans)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional regulation by RUNX3 (Caenorhabditis elegans)
Regulation of RUNX3 expression and activity (Caenorhabditis elegans)
RUNX3 binds SRC (Caenorhabditis elegans)
MyrG-p-Y419-SRC:RUNX3 [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
RUNX3 translocates to the nucleus (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
SRC phosphorylates RUNX3 (Caenorhabditis elegans)
MyrG-p-Y419-SRC:RUNX3 [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Hemostasis (Caenorhabditis elegans)
Platelet activation, signaling and aggregation (Caenorhabditis elegans)
Platelet Aggregation (Plug Formation) (Caenorhabditis elegans)
Integrin signaling (Caenorhabditis elegans)
Autophosphorylation of PTK2 at Y397 (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Autophosphorylation of SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
GRB2:SOS provides linkage to MAPK signaling for Integrins (Caenorhabditis elegans)
Interaction of SOS with GRB2 bound to FADK1 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Recruitment of GRB2 to p-PTK2 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Phosphorylation of pPTK2 by SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
SYK activation by SRC (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
SYK binds to integrin alphaIIb beta3 (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Translocation of PTK2 to Focal complexes (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Integrin signaling (Caenorhabditis elegans)
Autophosphorylation of PTK2 at Y397 (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Autophosphorylation of SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
GRB2:SOS provides linkage to MAPK signaling for Integrins (Caenorhabditis elegans)
Interaction of SOS with GRB2 bound to FADK1 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Recruitment of GRB2 to p-PTK2 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Phosphorylation of pPTK2 by SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
SYK activation by SRC (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
SYK binds to integrin alphaIIb beta3 (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Translocation of PTK2 to Focal complexes (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Intracellular signaling by second messengers (Caenorhabditis elegans)
PIP3 activates AKT signaling (Caenorhabditis elegans)
Negative regulation of the PI3K/AKT network (Caenorhabditis elegans)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Caenorhabditis elegans)
PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
Activator:PI3K [plasma membrane] (Caenorhabditis elegans)
ESRs:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Caenorhabditis elegans)
ESRs:STRN:ESTG:MyrG-pY419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
Activator:PI3K [plasma membrane] (Caenorhabditis elegans)
ESRs:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Caenorhabditis elegans)
ESRs:STRN:ESTG:MyrG-pY419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Signaling by Nuclear Receptors (Caenorhabditis elegans)
ESR-mediated signaling (Caenorhabditis elegans)
Extra-nuclear estrogen signaling (Caenorhabditis elegans)
PTK2 is recruited to methylated ESR1 (Caenorhabditis elegans)
Me260-ESR1:STRN:ESTG: MyrG-pY419 SRC:PI3Kalpha:pY-PTK2 [plasma membrane] (Caenorhabditis elegans)
Me260-ESR1:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Me260-ESR1:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by ERBB2 (Caenorhabditis elegans)
SRC family kinases phosphorylate ERBB2 (Caenorhabditis elegans)
p-Y419/420/426-N-myristoyl-SRC/FYN/YES1 [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Signaling by ERBB4 (Caenorhabditis elegans)
Downregulation of ERBB4 signaling (Caenorhabditis elegans)
ERBB4s80 binds to SRC (Caenorhabditis elegans)
ERBB4s80:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Nuclear signaling by ERBB4 (Caenorhabditis elegans)
Translocation of ERBB4s80 to the nucleus (Caenorhabditis elegans)
ERBB4s80:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Signaling by MET (Caenorhabditis elegans)
MET promotes cell motility (Caenorhabditis elegans)
MET activates PTK2 signaling (Caenorhabditis elegans)
MET phosphorylates PTK2 (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
SRC phosphorylates PTK2 (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
p-Y397-PTK2 binds SRC (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Signaling by PDGF (Caenorhabditis elegans)
Downstream signal transduction (Caenorhabditis elegans)
Activation of Src (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
phospho-MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:G5EE56
Reference Genes
BioGPS Gene:171722
ENSEMBL:WBGene00005077
Monarch:171722
NCBI Gene:171722
Wormbase:WBGene00005077
Reference Transcript
RefSeq:NM_001306492.1
RefSeq:NM_001306491.1
RefSeq:NM_058465.5
RefSeq:NM_001306493.1
Other Identifiers
171722
176215_at
176306_at
18463566
A_12_P116399
A_12_P145805
CE31390
CE_WBGene00005077_A
CE_WBGene00005077_B
CGZ0055280
GO:0003824
GO:0004672
GO:0004713
GO:0005515
GO:0005524
GO:0006468
GO:0016740
GO:0036211
GO:0140096
WBGene00005077
Y92H12A.1
Y92H12A.1_1101-1160_0.923_4_C
Y92H12A.1_1338-1397_0.928_2_B
Y92H12A.1_1461-1520_0.946_1_A
Y92H12A_1P00250
Y92H12A_1P00689
Y92H12A_1P00967
Participates
as a component of
Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] (Caenorhabditis elegans)
MyrG-p-Y419-SRC:RUNX3 [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Me260-ESR1:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Caenorhabditis elegans)
ERBB4s80:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
ESRs:STRN:ESTG:MyrG-pY419-SRC [plasma membrane] (Caenorhabditis elegans)
as an output of
SRC phosphorylates RUNX3 (Caenorhabditis elegans)
as an input of
RUNX3 binds SRC (Caenorhabditis elegans)
ERBB4s80 binds to SRC (Caenorhabditis elegans)
p-Y397-PTK2 binds SRC (Caenorhabditis elegans)
as a member of
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Caenorhabditis elegans)
p-Y419/420/426-N-myristoyl-SRC/FYN/YES1 [plasma membrane] (Caenorhabditis elegans)
This entity regulates
Negatively
RUNX3 translocates to the nucleus
(Caenorhabditis elegans)
Other forms of this molecule
FGR [extracellular region]
SRC-2 [cytosol]
FYN [cytosol]
LCK [cytosol]
SRC-1 [plasma membrane]
phospho-MyrG-p-Y426-YES1 [plasma membrane]
phospho-MyrG-p-Y420-FYN-1 [plasma membrane]
phospho-MyrG,p-Y530-SRC [plasma membrane]
phospho-p-Y420-FYN [cytosol]
LYN [cytosol]
phospho-p-Y419-SRC [cytosol]
FGR [cytosol]
YES1 [cytosol]
HCK [cytosol]
phospho-p-Y397-LYN [plasma membrane]
LYN [plasma membrane]
phospho-p-Y394-LCK [plasma membrane]
phospho-p-Y419-SRC-1 [plasma membrane]
MyrG-SRC [plasma membrane]
phospho-p-S21,Y420-FYN [cytosol]
phospho-p-Y419-SRC [cytosol]
SRC [cytosol]
FGR [secretory granule lumen]
Inferred From
MyrG-p-Y419-SRC [plasma membrane]
(Homo sapiens)
Modified Residues
Name
N-myristoylglycine at 2 (in Homo sapiens)
Coordinate
2
PsiMod Name
N-myristoylglycine [MOD:00068]
PsiMod Definition
A protein modification that effectively converts a glycine residue to N-myristoylglycine.
Name
O4'-phospho-L-tyrosine at 419 (in Homo sapiens)
Coordinate
419
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_001293420.1
,
NP_490866.4
,
NP_001293422.1
,
NP_001293421.1
IntEnz
2.7.10.2
PRO
G5EE56
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BIF4
4
ehs-1 [cytosol]
(R-CEL-8935900)
phospho-ehs-1 [cytosol]
(R-CEL-8867028)
ehs-1 [plasma membrane]
(R-CEL-182937)
ehs-1 [cytosol]
(R-CEL-182920)
0.553
3
UniProt:Q09442
1
sap-49 [nucleoplasm]
(R-CEL-71975)
0.553
3
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