Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
mlst-8 [cytosol]
Stable Identifier
R-CEL-165676
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
cytosol
Synonyms
MLST8, P91040
Locations in the PathwayBrowser
Expand all
Autophagy (Caenorhabditis elegans)
Macroautophagy (Caenorhabditis elegans)
Active MTORC1 binds the ULK1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
Active MTORC1 phosphorylates ULK1 (Caenorhabditis elegans)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
MTORC1 dissociates from ULK complex (Caenorhabditis elegans)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
Rheb in the MTORC1 complex hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Caenorhabditis elegans)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to starvation (Caenorhabditis elegans)
Amino acids regulate mTORC1 (Caenorhabditis elegans)
RRAGA,B hydrolyzes GTP (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1 binds RHEB:GTP (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional Regulation by TP53 (Caenorhabditis elegans)
Regulation of TP53 Activity (Caenorhabditis elegans)
Regulation of TP53 Expression and Degradation (Caenorhabditis elegans)
Regulation of TP53 Degradation (Caenorhabditis elegans)
TORC2 complex phosphorylates SGK1 (Caenorhabditis elegans)
TORC2 complex [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
TP53 Regulates Metabolic Genes (Caenorhabditis elegans)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Costimulation by the CD28 family (Caenorhabditis elegans)
CD28 co-stimulation (Caenorhabditis elegans)
CD28 dependent PI3K/Akt signaling (Caenorhabditis elegans)
TORC2 (mTOR) phosphorylates AKT at S473 (Caenorhabditis elegans)
TORC2 complex [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Intracellular signaling by second messengers (Caenorhabditis elegans)
PIP3 activates AKT signaling (Caenorhabditis elegans)
PTEN Regulation (Caenorhabditis elegans)
Regulation of PTEN gene transcription (Caenorhabditis elegans)
MAF1 translocates to the nucleus (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1 phosphorylates MAF1 (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
TORC2 (mTOR) phosphorylates AKT at S473 (Caenorhabditis elegans)
TORC2 complex [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
TORC2 complex phosphorylates SGK1 (Caenorhabditis elegans)
TORC2 complex [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
MTOR signalling (Caenorhabditis elegans)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Caenorhabditis elegans)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
Energy dependent regulation of mTOR by LKB1-AMPK (Caenorhabditis elegans)
AMPK phosphorylates Raptor in the mTORC1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
Formation of active mTORC1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1 phosphorylates AKT1S1 (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1-mediated signalling (Caenorhabditis elegans)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by VEGF (Caenorhabditis elegans)
VEGFA-VEGFR2 Pathway (Caenorhabditis elegans)
VEGFR2 mediated vascular permeability (Caenorhabditis elegans)
TORC2 (mTOR) phosphorylates AKT at S473 (Caenorhabditis elegans)
TORC2 complex [cytosol] (Caenorhabditis elegans)
mlst-8 [cytosol] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:P91040
Gene Names
mlst-8
Reference Genes
BioGPS Gene:182509 mlst-8
CTD Gene:182509 mlst-8
ENSEMBL:WBGene00015697
Monarch:182509 mlst-8
NCBI Gene:182509 mlst-8
UCSC:P91040 mlst-8
Wormbase:WBGene00015697
Reference Transcript
RefSeq:NM_001262780.1 mlst-8
Other Identifiers
182509
18465247
184715_at
A_12_P111808
C10H11.8
C10H11.8_172-231_0.874_40_C
C10H11.8_275-334_0.888_23_B
C10H11.8_684-743_0.936_3_A
C10H11_8P00237
C10H11_8P00538
C10H11_8P00826
CE08097
CE_WBGene00015697_A
CGZ0004139
GO:0005515
GO:0023052
GO:0031929
GO:0031931
GO:0031932
WBGene00015697
cea2.i.00421
Participates
as a component of
TORC2 complex [cytosol] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Caenorhabditis elegans)
Other forms of this molecule
mlst-8 [nucleoplasm]
Inferred From
MLST8 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001249709.1
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text