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P-TEFb complex [nucleoplasm]
Stable Identifier
R-CEL-112431
Type
Complex
Species
Caenorhabditis elegans
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional Regulation by TP53 (Caenorhabditis elegans)
TP53 Regulates Transcription of DNA Repair Genes (Caenorhabditis elegans)
CCNK:CDK12 binds RNA Pol II at DNA repair genes (Caenorhabditis elegans)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Caenorhabditis elegans)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Caenorhabditis elegans)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Caenorhabditis elegans)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Caenorhabditis elegans)
CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Caenorhabditis elegans)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Caenorhabditis elegans)
CDK12-phosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Caenorhabditis elegans)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Caenorhabditis elegans)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Caenorhabditis elegans)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Caenorhabditis elegans)
Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Caenorhabditis elegans)
CDK8:CCNC/ CDK9:CCNT [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
RNA Polymerase II Pre-transcription Events (Caenorhabditis elegans)
2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Caenorhabditis elegans)
Paused processive elongation complex [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Processive elongation complex [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Caenorhabditis elegans)
Processive elongation complex [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Abortive termination of elongation after arrest (Caenorhabditis elegans)
Aborted elongation complex after arrest [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Processive elongation complex [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Formation of P-TEFb complex (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Resumption of elongation after recovery from pausing (Caenorhabditis elegans)
Paused processive elongation complex [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Processive elongation complex [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
TFIIS-mediated recovery of elongation from arrest (Caenorhabditis elegans)
Processive elongation complex [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
RNA Polymerase II Transcription Elongation (Caenorhabditis elegans)
Addition of nucleotides leads to transcript elongation (Caenorhabditis elegans)
Elongation complex [nucleoplasm] (Caenorhabditis elegans)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Processive elongation complex [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Formation of RNA Pol II elongation complex (Caenorhabditis elegans)
Recruitment of elongation factors to form elongation complex (Caenorhabditis elegans)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Elongation complex [nucleoplasm] (Caenorhabditis elegans)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Pol II elongation complex moves on the template as transcript elongates (Caenorhabditis elegans)
Elongation complex prior to separation [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Processive elongation complex [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Separation of elongating transcript from template (Caenorhabditis elegans)
Elongation complex prior to separation [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
RNA polymerase II transcribes snRNA genes (Caenorhabditis elegans)
CBCAP complex binds 7-methylguanosine cap of snRNA (Caenorhabditis elegans)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Caenorhabditis elegans)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Caenorhabditis elegans)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Integrator complex processes the 3' end of snRNA (Caenorhabditis elegans)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Pre-snRNA is elongated and capped with 7-methylguanosine (Caenorhabditis elegans)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Caenorhabditis elegans)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Caenorhabditis elegans)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Signaling by TGFB family members (Caenorhabditis elegans)
Signaling by TGF-beta Receptor Complex (Caenorhabditis elegans)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Caenorhabditis elegans)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Caenorhabditis elegans)
Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Caenorhabditis elegans)
CDK8:CCNC/ CDK9:CCNT [nucleoplasm] (Caenorhabditis elegans)
P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CCNT1,CCNT2,CCNK [nucleoplasm]
(Caenorhabditis elegans)
CDK9 [nucleoplasm]
(Caenorhabditis elegans)
Participates
as a component of
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Caenorhabditis elegans)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
Aborted elongation complex after arrest [nucleoplasm] (Caenorhabditis elegans)
Paused processive elongation complex [nucleoplasm] (Caenorhabditis elegans)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Caenorhabditis elegans)
Elongation complex prior to separation [nucleoplasm] (Caenorhabditis elegans)
Processive elongation complex [nucleoplasm] (Caenorhabditis elegans)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Caenorhabditis elegans)
CDK12-phosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Caenorhabditis elegans)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Caenorhabditis elegans)
as an output of
Formation of P-TEFb complex (Caenorhabditis elegans)
as a member of
CDK8:CCNC/ CDK9:CCNT [nucleoplasm] (Caenorhabditis elegans)
Inferred From
P-TEFb complex [nucleoplasm]
(Homo sapiens)
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