botA HC disulfide bonded [synaptic vesicle membrane]

Stable Identifier
R-CBO-9616795
Type
Protein [EntityWithAccessionedSequence]
Species
Clostridium botulinum
Compartment
Synonyms
BoNT/A HC disulfide bonded, BoNT Heavy chain Type A
GO Cellular Component
botA HC disulfide bonded [synaptic vesicle membrane] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
6370252 Partial amino acid sequence of the heavy and light chains of botulinum neurotoxin type A

Schmidt, JJ, Sathyamoorthy, V, DasGupta, BR

Biochem. Biophys. Res. Commun. 1984
3178218 Botulinum neurotoxin type A: cleavage of the heavy chain into two halves and their partial sequences

Sathyamoorthy, V, DasGupta, BR, Foley, J, Niece, RL

Arch. Biochem. Biophys. 1988
External Reference Information
External Reference
Gene Names
botA, atx, bonT
Chain
initiator methionine:1, chain:2-1296, chain:2-448, chain:449-1296
Participates
Other forms of this molecule
Modified Residues
Name
Inter-chain Crosslink via L-cystine (cross-link) at 454 and 430
Coordinate
454
PsiMod Name
PsiMod Definition
A protein modification that effectively cross-links two L-cysteine residues to form L-cystine.
Disease
Name Identifier Synonyms
botulism DOID:11976 Botulism (disorder), Intoxication with Clostridium botulinum toxin, Botulism, Infection due to clostridium botulinum, Botulism, Foodborne botulism, botulism, Botulism, Botulism, Botulism, Food poisoning due to Clostridium botulinum, Botulism poisoning
Interactors (3)
Cite Us!