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SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol]
Stable Identifier
R-BTA-9766649
Type
Complex
Species
Bos taurus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to chemical stress (Bos taurus)
KEAP1-NFE2L2 pathway (Bos taurus)
CUL3:RBX1 ubiquitinates KEAP1 (Bos taurus)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Bos taurus)
MAP1LC3B binds KEAP1 and SQSTM1 (Bos taurus)
MAP1LC3B:SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Bos taurus)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Bos taurus)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Bos taurus)
RBX1:CUL3 dissociates from forming autophagosome (Bos taurus)
MAP1LC3B:SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Bos taurus)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
SESN1,2 [cytosol]
(Bos taurus)
ub-K420 p-S349 SQSTM1 oligomer [cytosol]
(Bos taurus)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol]
(Bos taurus)
Participates
as an input of
MAP1LC3B binds KEAP1 and SQSTM1 (Bos taurus)
as an output of
CUL3:RBX1 ubiquitinates KEAP1 (Bos taurus)
as a component of
MAP1LC3B:SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Bos taurus)
Inferred From
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol]
(Homo sapiens)
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