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DTL [nucleoplasm]
Stable Identifier
R-BTA-975985
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
DTL, E1BJV8
Locations in the PathwayBrowser
Expand all
DNA Repair (Bos taurus)
DNA Damage Bypass (Bos taurus)
Recognition of DNA damage by PCNA-containing replication complex (Bos taurus)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Bos taurus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Bos taurus)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Bos taurus)
DTL [nucleoplasm] (Bos taurus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Bos taurus)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Bos taurus)
DTL [nucleoplasm] (Bos taurus)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Bos taurus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Bos taurus)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Bos taurus)
DTL [nucleoplasm] (Bos taurus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Bos taurus)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Bos taurus)
DTL [nucleoplasm] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Neddylation (Bos taurus)
AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Bos taurus)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Bos taurus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Bos taurus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Bos taurus)
DCAF protein [nucleoplasm] (Bos taurus)
DTL [nucleoplasm] (Bos taurus)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Bos taurus)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Bos taurus)
DCAF protein [nucleoplasm] (Bos taurus)
DTL [nucleoplasm] (Bos taurus)
CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Bos taurus)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Bos taurus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Bos taurus)
DCAF protein [nucleoplasm] (Bos taurus)
DTL [nucleoplasm] (Bos taurus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Bos taurus)
DCAF protein [nucleoplasm] (Bos taurus)
DTL [nucleoplasm] (Bos taurus)
COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Bos taurus)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Bos taurus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Bos taurus)
DCAF protein [nucleoplasm] (Bos taurus)
DTL [nucleoplasm] (Bos taurus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Bos taurus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Bos taurus)
DCAF protein [nucleoplasm] (Bos taurus)
DTL [nucleoplasm] (Bos taurus)
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Bos taurus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Bos taurus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Bos taurus)
DCAF protein [nucleoplasm] (Bos taurus)
DTL [nucleoplasm] (Bos taurus)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Bos taurus)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Bos taurus)
DCAF protein [nucleoplasm] (Bos taurus)
DTL [nucleoplasm] (Bos taurus)
NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Bos taurus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Bos taurus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Bos taurus)
DCAF protein [nucleoplasm] (Bos taurus)
DTL [nucleoplasm] (Bos taurus)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Bos taurus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Bos taurus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Bos taurus)
DCAF protein [nucleoplasm] (Bos taurus)
DTL [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:E1BJV8
Gene Names
DTL
Reference Genes
ENSEMBL:ENSBTAG00000018142.6
ENSEMBL:ENSBTAG00000018142.7 DTL
Other Identifiers
GO:0000278
GO:0005634
GO:0007095
GO:0023052
GO:0030163
GO:0030674
GO:0043161
GO:0043226
GO:0048511
GO:0060090
Participates
as a member of
DCAF protein [nucleoplasm] (Bos taurus)
as a component of
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Bos taurus)
Inferred From
DTL [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000143476
Ensembl
ENSBTAT00000024147
,
ENSBTAP00000024147
,
ENSBTAG00000018142
VGNC
28230
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