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MDK:p-7Y ALK dimer [plasma membrane]
Stable Identifier
R-BTA-9700017
Type
Complex
Species
Bos taurus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by ALK (Bos taurus)
ALK autophosphorylation (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK binds JAK3 (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK:JAK3 [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK binds PLCG1 (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK:PLCG1 [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK binds SHC1 (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK:SHC1 [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK dimer binds IRS1 (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK:IRS1 [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK phosphorylates IRS1 (Bos taurus)
Active ALK:IRS1 [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK:pY-IRS1 [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK phosphorylates JAK3 (Bos taurus)
Active ALK:JAK3 [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK:p-Y980 JAK3 [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK phosphorylates PLCG1 (Bos taurus)
Active ALK:PLCG1 [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK:p-4Y PLCG1 [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK phosphorylates SHC1 (Bos taurus)
Active ALK:SHC1 [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK:p-3Y SHC1 [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK recruits PI3K (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK:PI3K [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
MDK and PTN in ALK signaling (Bos taurus)
PTPRZ dephosphorylates ligand-bound ALK dimers (Bos taurus)
(PTN,MDK):p-7Y ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
PI3K synthesizes PIP3 downstream of ALK (Bos taurus)
Active ALK:PI3K [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
PTPN6 dephosphorylates JAK3 (Bos taurus)
Active ALK:JAK3 [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
Active ALK:p-Y980 JAK3 [plasma membrane] (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
STAT3 is phosphorylated downstream of active ALK (Bos taurus)
Active ALK dimer [plasma membrane] (Bos taurus)
MDK:p-7Y ALK dimer [plasma membrane] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
MDK [extracellular region]
(Bos taurus)
p-7Y ALK dimer [plasma membrane]
(Bos taurus)
Participates
as a member of
(PTN,MDK):p-7Y ALK dimer [plasma membrane] (Bos taurus)
as a candidate of
Active ALK dimer [plasma membrane] (Bos taurus)
Inferred From
MDK:p-7Y ALK dimer [plasma membrane]
(Homo sapiens)
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