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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
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Diseases
Cytomics
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FAQ
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Citing us
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NRAS [plasma membrane]
Stable Identifier
R-BTA-9647910
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
plasma membrane
Synonyms
S-Farn-Me PalmS NRAS, A5D7R9
Locations in the PathwayBrowser
Expand all
Developmental Biology (Bos taurus)
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
NCAM signaling for neurite out-growth (Bos taurus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Hemostasis (Bos taurus)
Cell surface interactions at the vascular wall (Bos taurus)
Tie2 Signaling (Bos taurus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Signaling by the B Cell Receptor (BCR) (Bos taurus)
Downstream signaling events of B Cell Receptor (BCR) (Bos taurus)
Activation of RAS in B cells (Bos taurus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
FLT3 Signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Innate Immune System (Bos taurus)
DAP12 interactions (Bos taurus)
DAP12 signaling (Bos taurus)
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Fc epsilon receptor (FCERI) signaling (Bos taurus)
FCERI mediated MAPK activation (Bos taurus)
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signal Transduction (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
Intrinsic nucleotide exchange on RAS (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
MAP2K and MAPK activation (Bos taurus)
Dissociation of RAS:RAF complex (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Dual mechanism MAPK inhibitors bind MAPKs (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
MAP2Ks and MAPKs bind to the activated RAF complex (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
MAP2Ks phosphorylate MAPKs (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
RAF phosphorylates MAP2K dimer (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Negative regulation of MAPK pathway (Bos taurus)
BRAP autoubiquitinates (Bos taurus)
p21 RAS:GTP:BRAP [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP:ub-BRAP [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
BRAP binds RAS:GTP (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP:BRAP [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
PEBP1 binds activated RAF1 (Bos taurus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
PP2A dephosphorylates RAF1 (Bos taurus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
PP5 dephosphorylates RAF1 S338 (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
RAF activation (Bos taurus)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Phosphorylation of RAF (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Raf dimer inhibitors bind RAF heterodimers (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
RAS GEFs promote RAS nucleotide exchange (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
RAS processing (Bos taurus)
RAS proteins are depalmitoylated (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
mature RAS proteins translocate to plasma membrane (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
mature p21 RAS binds GDP (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
RAS:GTP binds PI3K (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP:PI3K [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (q) signalling events (Bos taurus)
Gastrin-CREB signalling pathway via PKC and MAPK (Bos taurus)
EGFR Transactivation by Gastrin (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by Non-Receptor Tyrosine Kinases (Bos taurus)
Signaling by PTK6 (Bos taurus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Bos taurus)
RASA1 binds RAS:GTP (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP:RASA1 [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
RASA1 stimulates RAS GTPase activity (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP:RASA1 [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
Extra-nuclear estrogen signaling (Bos taurus)
Estrogen-stimulated signaling through PRKCZ (Bos taurus)
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
PRKCZ recruits RAS in response to estrogen stimulation (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by EGFR (Bos taurus)
GRB2 events in EGFR signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
SHC1 events in EGFR signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by ERBB2 (Bos taurus)
GRB2 events in ERBB2 signaling (Bos taurus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by ERBB4 (Bos taurus)
SHC1 events in ERBB4 signaling (Bos taurus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by FGFR (Bos taurus)
Signaling by FGFR1 (Bos taurus)
Downstream signaling of activated FGFR1 (Bos taurus)
FRS-mediated FGFR1 signaling (Bos taurus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
SHC-mediated cascade:FGFR1 (Bos taurus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by FGFR2 (Bos taurus)
Downstream signaling of activated FGFR2 (Bos taurus)
FRS-mediated FGFR2 signaling (Bos taurus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
SHC-mediated cascade:FGFR2 (Bos taurus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by FGFR3 (Bos taurus)
Downstream signaling of activated FGFR3 (Bos taurus)
FRS-mediated FGFR3 signaling (Bos taurus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
SHC-mediated cascade:FGFR3 (Bos taurus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by FGFR4 (Bos taurus)
Downstream signaling of activated FGFR4 (Bos taurus)
FRS-mediated FGFR4 signaling (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
SHC-mediated cascade:FGFR4 (Bos taurus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by MET (Bos taurus)
MET activates RAS signaling (Bos taurus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by NTRKs (Bos taurus)
Signaling by NTRK1 (TRKA) (Bos taurus)
Signalling to ERKs (Bos taurus)
Signalling to RAS (Bos taurus)
p38MAPK events (Bos taurus)
Ral-GDS binds to Ras-GTP (Bos taurus)
Ras-GTP:RalGDS complex [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by PDGF (Bos taurus)
Downstream signal transduction (Bos taurus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by SCF-KIT (Bos taurus)
Activation of RAS by p-KIT bound SOS1 (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
VEGFR2 mediated cell proliferation (Bos taurus)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Bos taurus)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
mature p21 RAS [plasma membrane] (Bos taurus)
NRAS [plasma membrane] (Bos taurus)
External Reference Information
External Reference
UniProt:A5D7R9
Gene Names
NRAS
Reference Genes
BioGPS Gene:506322 NRAS
ENSEMBL:ENSBTAG00000046797.2
KEGG:bta:506322 NRAS
Monarch:506322 NRAS
NCBI Gene:506322 NRAS
UCSC:A5D7R9 NRAS
Reference Transcript
RefSeq:NM_001097989.1 NRAS
Other Identifiers
506322
GO:0000139
GO:0001938
GO:0003824
GO:0003924
GO:0005525
GO:0005737
GO:0005794
GO:0005886
GO:0007165
GO:0007265
GO:0016020
GO:0016787
GO:0019003
GO:0043226
GO:0044877
Participates
as a member of
mature p21 RAS [plasma membrane] (Bos taurus)
Other forms of this molecule
NRAS [tertiary granule membrane]
NRAS [plasma membrane]
NRAS [plasma membrane]
NRAS [Golgi membrane]
NRAS [endoplasmic reticulum membrane]
NRAS [endoplasmic reticulum membrane]
NRAS [endoplasmic reticulum membrane]
NRAS [cytosol]
Inferred From
S-Farn-Me PalmS NRAS [plasma membrane]
(Homo sapiens)
Modified Residues
Name
S-farnesyl-L-cysteine methyl ester at 186 (in Homo sapiens)
Coordinate
186
PsiMod Name
S-farnesyl-L-cysteine methyl ester
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-farnesyl-L-cysteine methyl ester.
Name
S-palmitoyl-L-cysteine at 181 (in Homo sapiens)
Coordinate
181
PsiMod Name
S-palmitoyl-L-cysteine [MOD:00115]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.
Cross References
RefSeq
NP_001091458.1
ENSEMBL
ENSBTAP00000012897
,
ENSBTAT00000012897
VGNC
32253
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