Reactome | ATP6V0E1 [lysosomal membrane]

ATP6V0E1 [lysosomal membrane]

Stable Identifier

R-BTA-9640180

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

lysosomal membrane

Synonyms

ATP6V0E1, P81103

Locations in the PathwayBrowser

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Cellular responses to stimuli (Bos taurus)

- Cellular responses to stress (Bos taurus)
  - Cellular response to starvation (Bos taurus)
    - Amino acids regulate mTORC1 (Bos taurus)
      - RRAGA,B exchanges GDP for GTP (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
      - RRAGA,B hydrolyzes GTP (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
      - RRAGC,D exchanges GTP for GDP (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
      - RRAGC,D hydrolyzes GTP (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
      - mTORC1 binds RHEB:GTP (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
      - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0E [lysosomal membrane] (Bos taurus)
        
        ATP6V0E1 [lysosomal membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:P81103

Gene Names

ATP6V0E1

Reference Genes

BioGPS Gene:338075 ATP6V0E1

ENSEMBL:ENSBTAG00000015100

ENSEMBL:ENSBTAG00000015100.3 ATP6V0E1

KEGG Gene (Bos taurus):338075 ATP6V0E1

Monarch:338075 ATP6V0E1

NCBI Gene:338075 ATP6V0E1

Reference Transcript

RefSeq:NM_001034050.2 ATP6V0E1

Other Identifiers

338075

GO:0005215

GO:0033179

GO:0046961

GO:0055085

GO:0140657

GO:1902600

Participates

as a member of

ATP6V0E [lysosomal membrane] (Bos taurus)

Other forms of this molecule

ATP6V0E1 [phagocytic vesicle membrane]

ATP6V0E1 [endosome membrane]

Inferred From

ATP6V0E1 [lysosomal membrane] (Homo sapiens)

Cross References

RefSeq

NP_001029222.1

OpenTargets

ENSG00000113732

Ensembl

ENSBTAG00000015100, ENSBTAT00000020094, ENSBTAP00000020094

VGNC

26314

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