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EIF4A3 [cytosol]
Stable Identifier
R-BTA-927868
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
Q2NL22
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Interferon Signaling (Bos taurus)
Antiviral mechanism by IFN-stimulated genes (Bos taurus)
ISG15 antiviral mechanism (Bos taurus)
Competitive inhibition of translation initiation by ISGylated 4EHP (Bos taurus)
EIF4F [cytosol] (Bos taurus)
eIF4A [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
eIF4F:mRNA [cytosol] (Bos taurus)
EIF4F [cytosol] (Bos taurus)
eIF4A [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
Metabolism of RNA (Bos taurus)
Deadenylation-dependent mRNA decay (Bos taurus)
Deadenylation of mRNA (Bos taurus)
CCR4-NOT complex deadenylates mRNA (Bos taurus)
Partially Deadenylated mRNA Complex [cytosol] (Bos taurus)
eIF4A [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
eIF4A [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
PAN2-PAN3 complex partially deadenylates mRNA (Bos taurus)
Partially Deadenylated mRNA Complex [cytosol] (Bos taurus)
eIF4A [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
Translatable mRNA Complex [cytosol] (Bos taurus)
eIF4A [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
PARN deadenylates mRNA (Bos taurus)
Partially Deadenylated mRNA Complex [cytosol] (Bos taurus)
eIF4A [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
eIF4A [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
Nonsense-Mediated Decay (NMD) (Bos taurus)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Bos taurus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Bos taurus)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Bos taurus)
Core Exon Junction Complex (Core EJC) [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Bos taurus)
Core Exon Junction Complex (Core EJC) [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
SMG6 hydrolyzes mRNA with premature termination codon (Bos taurus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Bos taurus)
Core Exon Junction Complex (Core EJC) [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Bos taurus)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Bos taurus)
Core Exon Junction Complex (Core EJC) [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Bos taurus)
Core Exon Junction Complex (Core EJC) [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Bos taurus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Bos taurus)
Core Exon Junction Complex (Core EJC) [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Bos taurus)
Core Exon Junction Complex (Core EJC) [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
Processing of Capped Intron-Containing Pre-mRNA (Bos taurus)
Transport of Mature Transcript to Cytoplasm (Bos taurus)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Bos taurus)
Transport of the export-competent mRNP complex through the NPC (Bos taurus)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Bos taurus)
EJC [cytosol] (Bos taurus)
Core Exon Junction Complex (Core EJC) [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
mRNP complex dissociates from cytosolic face of NPC (Bos taurus)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Bos taurus)
EJC [cytosol] (Bos taurus)
Core Exon Junction Complex (Core EJC) [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
mRNA:CBC:EJC:POLDIP3 [cytosol] (Bos taurus)
EJC [cytosol] (Bos taurus)
Core Exon Junction Complex (Core EJC) [cytosol] (Bos taurus)
EIF4A3 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:Q2NL22
Reference Genes
BioGPS Gene:515145
ENSEMBL:ENSBTAG00000016023
ENSEMBL:ENSBTAG00000016023.5
KEGG Gene (Bos taurus):515145
Monarch:515145
NCBI Gene:515145
Reference Transcript
RefSeq:NM_001046188.2
Other Identifiers
GO:0000166
GO:0000184
GO:0000381
GO:0000398
GO:0003676
GO:0003723
GO:0003724
GO:0003729
GO:0003824
GO:0004386
GO:0005524
GO:0005634
GO:0005654
GO:0005681
GO:0005730
GO:0005737
GO:0006364
GO:0006397
GO:0006417
GO:0008143
GO:0008380
GO:0016071
GO:0016607
GO:0016787
GO:0016887
GO:0017148
GO:0035145
GO:0042254
GO:0043226
GO:0045727
GO:0048701
GO:0048856
GO:0051028
GO:0071006
GO:0071013
GO:0140098
GO:0140657
GO:2000622
Participates
as a component of
Core Exon Junction Complex (Core EJC) [cytosol] (Bos taurus)
as a member of
eIF4A [cytosol] (Bos taurus)
Other forms of this molecule
EIF4A3 [nucleoplasm]
Inferred From
EIF4A3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001039653.1
IntEnz
3.6.4.13
Ensembl
ENSBTAG00000016023
,
ENSBTAT00000021327
,
ENSBTAP00000021327
VGNC
28406
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