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RAPGEF1 [cytosol]
Stable Identifier
R-BTA-913472
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
RAPGEF1, A0A3Q1LXN8
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Bos taurus)
Regulation of signaling by CBL (Bos taurus)
CBL:CRKL binds RAPGEF1 (Bos taurus)
RAPGEF1 [cytosol] (Bos taurus)
p(Y700,731,774)-CBL:CRK:RAPGEF1 [cytosol] (Bos taurus)
RAPGEF1 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by Erythropoietin (Bos taurus)
Erythropoietin activates RAS (Bos taurus)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:VAV1 (Bos taurus)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:p-Y-SHC1 [plasma membrane] (Bos taurus)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1 [plasma membrane] (Bos taurus)
p-CRKL:RAPGEF1 [cytosol] (Bos taurus)
RAPGEF1 [cytosol] (Bos taurus)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:p-Y-SHC1:GRB2:VAV1 [plasma membrane] (Bos taurus)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:p-Y-SHC1 [plasma membrane] (Bos taurus)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1 [plasma membrane] (Bos taurus)
p-CRKL:RAPGEF1 [cytosol] (Bos taurus)
RAPGEF1 [cytosol] (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by MET (Bos taurus)
MET promotes cell motility (Bos taurus)
MET activates RAP1 and RAC1 (Bos taurus)
RAPGEF1 activates RAP1 (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Bos taurus)
RAPGEF1 [cytosol] (Bos taurus)
RAPGEF1 [cytosol] (Bos taurus)
RAPGEF1 binds CRK,CRKL (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Bos taurus)
RAPGEF1 [cytosol] (Bos taurus)
RAPGEF1 [cytosol] (Bos taurus)
Signaling by NTRKs (Bos taurus)
Signaling by NTRK1 (TRKA) (Bos taurus)
Signalling to ERKs (Bos taurus)
Prolonged ERK activation events (Bos taurus)
Frs2-mediated activation (Bos taurus)
p-FRS2:CRKL binds C3G (Bos taurus)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane] (Bos taurus)
RAPGEF1 [cytosol] (Bos taurus)
RAPGEF1 [cytosol] (Bos taurus)
Signaling by PDGF (Bos taurus)
Downstream signal transduction (Bos taurus)
p130Cas and C3G bind PDGFR bound Crk (Bos taurus)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Bos taurus)
RAPGEF1 [cytosol] (Bos taurus)
RAPGEF1 [cytosol] (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase cycle (Bos taurus)
RAC3 GTPase cycle (Bos taurus)
RAC3 binds effectors at the plasma membrane (Bos taurus)
RAC3 effectors [cytosol] (Bos taurus)
RAPGEF1 [cytosol] (Bos taurus)
RAC3:GTP:RAC3 effectors [plasma membrane] (Bos taurus)
RAC3 effectors [cytosol] (Bos taurus)
RAPGEF1 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A3Q1LXN8
Gene Names
RAPGEF1
Reference Genes
ENSEMBL:ENSBTAG00000020791.6
UCSC:A0A3Q1LXN8 RAPGEF1
Other Identifiers
520454
GO:0001568
GO:0005085
GO:0007155
GO:0007265
GO:0043226
GO:0043231
GO:0043491
GO:0046580
GO:0048008
GO:0048856
GO:0051898
GO:0060070
GO:0061351
GO:0070371
GO:0070373
GO:0090090
GO:0098609
GO:0098772
GO:2000178
Participates
as a component of
p-CRKL:RAPGEF1 [cytosol] (Bos taurus)
p(Y700,731,774)-CBL:CRK:RAPGEF1 [cytosol] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Bos taurus)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Bos taurus)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane] (Bos taurus)
as a candidate of
RAC3 effectors [cytosol] (Bos taurus)
as an input of
CBL:CRKL binds RAPGEF1 (Bos taurus)
RAPGEF1 binds CRK,CRKL (Bos taurus)
p130Cas and C3G bind PDGFR bound Crk (Bos taurus)
p-FRS2:CRKL binds C3G (Bos taurus)
Inferred From
RAPGEF1 [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
ENSBTAT00000066818
,
ENSBTAP00000060297
VGNC
33722
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