Reactome | Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane]

Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane]

Stable Identifier

R-BTA-912533

Type

Set [DefinedSet]

Species

Bos taurus

Compartment

plasma membrane

Locations in the PathwayBrowser

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Participants

members

IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)

Participates

as an input of

Gab2 binds the p85 subunit of Class 1A PI3 kinases (Bos taurus)

as an output of

SHC1 mediates cytokine-induced phosphorylation of GAB2 (Bos taurus)

Inferred From

Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Homo sapiens)

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