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p-JAK1:p-JAK2:p-TYK2 [cytosol]
Stable Identifier
R-BTA-8950211
Type
Set [CandidateSet]
Species
Bos taurus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-12 family signaling (Bos taurus)
Interleukin-27 signaling (Bos taurus)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Bos taurus)
IL27:EBI3:IL27RA:p-JAK1:IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
IL6ST:(p-JAK1:p-JAK2:p-TYK2) [plasma membrane] (Bos taurus)
p-JAK1:p-JAK2:p-TYK2 [cytosol] (Bos taurus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
p-JAK1:p-JAK2:p-TYK2 [cytosol] (Bos taurus)
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Bos taurus)
IL27:EBI3:IL27RA:p-JAK1:IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
IL6ST:(p-JAK1:p-JAK2:p-TYK2) [plasma membrane] (Bos taurus)
p-JAK1:p-JAK2:p-TYK2 [cytosol] (Bos taurus)
STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex (Bos taurus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
p-JAK1:p-JAK2:p-TYK2 [cytosol] (Bos taurus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] (Bos taurus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
p-JAK1:p-JAK2:p-TYK2 [cytosol] (Bos taurus)
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Bos taurus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] (Bos taurus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
p-JAK1:p-JAK2:p-TYK2 [cytosol] (Bos taurus)
p-Y701-STAT1:p-Y705-STAT3:IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
p-JAK1:p-JAK2:p-TYK2 [cytosol] (Bos taurus)
p-Y701-STAT1 and p-Y705-STAT3 dissociate from IL27:IL27 receptor (Bos taurus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] (Bos taurus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
p-JAK1:p-JAK2:p-TYK2 [cytosol] (Bos taurus)
p-Y701-STAT1:p-Y705-STAT3:IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
p-JAK1:p-JAK2:p-TYK2 [cytosol] (Bos taurus)
Participants
members
phospho-JAK2 [cytosol]
(Bos taurus)
phospho-TYK2 [cytosol]
(Bos taurus)
candidates
phospho-JAK1 [cytosol]
(Bos taurus)
Participates
as a component of
p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
IL6ST:(p-JAK1:p-JAK2:p-TYK2) [plasma membrane] (Bos taurus)
Inferred From
p-JAK1:p-JAK2:p-TYK2 [cytosol]
(Homo sapiens)
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