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2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane]
Stable Identifier
R-BTA-8854160
Type
Complex
Species
Bos taurus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Developmental Biology (Bos taurus)
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
RET signaling (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:FRS2 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB7,GRB10 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:PLCG1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:RET interactors [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:SRC-1,RAP1GAP [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:DOK1,DOK2,DOK4,DOK5,DOK6 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
RET tyrosine phosphorylation (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
SHC1 in the RET complex is phosphorylated (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:PTPN11 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
p-5Y-RET complexes bind GRB2 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
p-5Y-RET:GDNF:GFRA complexes with and without p-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
Signal Transduction (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
RAS GEFs promote RAS nucleotide exchange (Bos taurus)
RAS GEFs [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
p-5Y-RET:GFRA:GDNF complexes [plasma membrane]
(Bos taurus)
Participates
as an input of
2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 (Bos taurus)
as a component of
2x p-5Y-RET:GDNF:GFRA complexes:GRB7,GRB10 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:PLCG1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:RET interactors [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:FRS2 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:DOK1,DOK2,DOK4,DOK5,DOK6 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:SRC-1,RAP1GAP [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1 [plasma membrane] (Bos taurus)
as a member of
p-5Y-RET:GDNF:GFRA complexes with and without p-SHC1 [plasma membrane] (Bos taurus)
as an output of
RET tyrosine phosphorylation (Bos taurus)
Inferred From
2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane]
(Homo sapiens)
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