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STAT2 [cytosol]
Stable Identifier
R-BTA-882029
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
STAT2, E1B8Z4
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Interferon Signaling (Bos taurus)
Interferon alpha/beta signaling (Bos taurus)
Activation of JAK kinases (Bos taurus)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Bos taurus)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
Formation of p-STAT1 homodimer (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFN alpha/beta binds to IFNAR2 (Bos taurus)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Bos taurus)
IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNAR2:JAK1:STAT2:type 1 interferon analogs [plasma membrane] (Bos taurus)
IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Bos taurus)
IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Bos taurus)
IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Bos taurus)
IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNAR2:JAK1:STAT2:type 1 interferon analogs [plasma membrane] (Bos taurus)
IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
Phosphorylation of INFAR1 by TYK2 (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
Phosphorylation of STAT2 (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
Recruitment of IFNAR1 (Bos taurus)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Bos taurus)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
Recruitment of STAT2 to p-IFNAR1 (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
multiubiquitinated STAT2 [cytosol] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
Regulation of IFNA/IFNB signaling (Bos taurus)
Dephosphorylation of JAK1 by SHP1 (Bos taurus)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Bos taurus)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
Dephosphorylation of STAT1 by SHP2 (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:STAT1 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
Dephosphorylation of TYK2 by PTP1B (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
Release of p-STAT2:p-STAT1 dimer (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-20 family signaling (Bos taurus)
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Bos taurus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5 [plasma membrane] (Bos taurus)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 (Bos taurus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5 [plasma membrane] (Bos taurus)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Bos taurus)
STAT2 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:E1B8Z4
Gene Names
STAT2
Reference Genes
BioGPS Gene:511023 STAT2
ENSEMBL:ENSBTAG00000004380.5
ENSEMBL:ENSBTAG00000004380.6 STAT2
KEGG Gene (Bos taurus):511023 STAT2
Monarch:511023 STAT2
NCBI Gene:511023 STAT2
Reference Transcript
RefSeq:XM_005206561.3 STAT2
RefSeq:NM_001205689.1 STAT2
Other Identifiers
GO:0000978
GO:0000981
GO:0001932
GO:0002376
GO:0003677
GO:0003700
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006357
GO:0006952
GO:0007005
GO:0007165
GO:0007259
GO:0010033
GO:0023052
GO:0036211
GO:0042127
GO:0042802
GO:0043226
GO:0043434
GO:0044389
GO:0045944
GO:0048856
GO:0051607
GO:0060337
GO:0060339
GO:0070721
GO:0090140
GO:0098542
GO:0140110
Participates
as a member of
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Bos taurus)
as an input of
Recruitment of STAT2 to p-IFNAR1 (Bos taurus)
as a component of
IFNAR2:JAK1:STAT2 [plasma membrane] (Bos taurus)
multiubiquitinated STAT2 [cytosol] (Bos taurus)
STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Bos taurus)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Bos taurus)
Other forms of this molecule
phospho-STAT2 [cytosol]
phospho-STAT2 [nucleoplasm]
phospho-STAT2 [cytosol]
Inferred From
STAT2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_005206618.1
,
NP_001192618.1
OpenTargets
ENSG00000170581
Ensembl
ENSBTAT00000005749
,
ENSBTAP00000005749
,
ENSBTAG00000004380
VGNC
35370
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