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RB1 [nucleoplasm]
Stable Identifier
R-BTA-68642
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
RB1, F1MD46
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Prophase (Bos taurus)
Condensation of Prophase Chromosomes (Bos taurus)
Condensin II complex binds H4K20me1-containing nucleosomes (Bos taurus)
Condensin II:RB1 [nucleoplasm] (Bos taurus)
RB1 [nucleoplasm] (Bos taurus)
RB1 binds condensin II (Bos taurus)
Condensin II:RB1 [nucleoplasm] (Bos taurus)
RB1 [nucleoplasm] (Bos taurus)
RB1 [nucleoplasm] (Bos taurus)
Mitotic G1 phase and G1/S transition (Bos taurus)
G1 Phase (Bos taurus)
Cyclin D associated events in G1 (Bos taurus)
Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Bos taurus)
RB1 [nucleoplasm] (Bos taurus)
RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Bos taurus)
RB1 [nucleoplasm] (Bos taurus)
RB1:E2F1,E2F2,E2F3:TFDP1,TFDP2: [nucleoplasm] (Bos taurus)
RB1 [nucleoplasm] (Bos taurus)
RB1 translocates to the nucleus (Bos taurus)
RB1 [nucleoplasm] (Bos taurus)
G1/S Transition (Bos taurus)
E2F mediated regulation of DNA replication (Bos taurus)
Inhibition of replication initiation of damaged DNA by RB1/E2F1 (Bos taurus)
PP2A mediated localization of RB1 protein in chromatin (Bos taurus)
RB1:RNA primer-DNA primer:origin duplex with DNA damage [nucleoplasm] (Bos taurus)
RB1 [nucleoplasm] (Bos taurus)
Regulation of mitotic cell cycle (Bos taurus)
APC/C-mediated degradation of cell cycle proteins (Bos taurus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Bos taurus)
APC/C:Cdh1 polyubiquitinates SKP2 (Bos taurus)
PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Bos taurus)
RB1 [nucleoplasm] (Bos taurus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Bos taurus)
RB1 [nucleoplasm] (Bos taurus)
APC/C:Cdh1-mediated degradation of Skp2 (Bos taurus)
PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Bos taurus)
RB1 [nucleoplasm] (Bos taurus)
RB1 [nucleoplasm] (Bos taurus)
RB1 recruits APC/C:Cdh1 complex to SKP2 (Bos taurus)
RB1 [nucleoplasm] (Bos taurus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Bos taurus)
RB1 [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:F1MD46
Gene Names
RB1
Reference Genes
ENSEMBL:ENSBTAG00000006640.5
ENSEMBL:ENSBTAG00000006640.6 RB1
Other Identifiers
534712
GO:0000082
GO:0000122
GO:0000278
GO:0000785
GO:0000977
GO:0001558
GO:0001894
GO:0002062
GO:0002376
GO:0003180
GO:0003677
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005819
GO:0005856
GO:0006325
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0006915
GO:0006954
GO:0007049
GO:0007059
GO:0007224
GO:0007265
GO:0007346
GO:0008024
GO:0008283
GO:0008285
GO:0010629
GO:0012501
GO:0014009
GO:0016605
GO:0019899
GO:0019900
GO:0023052
GO:0030154
GO:0030182
GO:0030198
GO:0030308
GO:0031134
GO:0031175
GO:0031507
GO:0031625
GO:0032869
GO:0034088
GO:0034349
GO:0035189
GO:0035914
GO:0042551
GO:0042802
GO:0043226
GO:0043353
GO:0045445
GO:0045651
GO:0045786
GO:0045842
GO:0045879
GO:0045892
GO:0045930
GO:0045944
GO:0048565
GO:0048667
GO:0048856
GO:0050673
GO:0050680
GO:0050728
GO:0051146
GO:0051172
GO:0051219
GO:0051276
GO:0051301
GO:0051402
GO:0051726
GO:0060253
GO:0060255
GO:0061629
GO:0061676
GO:0061793
GO:0071459
GO:0071466
GO:0080090
GO:0097284
GO:0097718
GO:0120163
GO:0140014
GO:0140297
GO:1903055
GO:1904028
GO:1904761
GO:2000045
GO:2000134
Participates
as an input of
RB1 binds condensin II (Bos taurus)
RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Bos taurus)
RB1 recruits APC/C:Cdh1 complex to SKP2 (Bos taurus)
Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Bos taurus)
as a component of
Condensin II:RB1 [nucleoplasm] (Bos taurus)
RB1:RNA primer-DNA primer:origin duplex with DNA damage [nucleoplasm] (Bos taurus)
RB1:E2F1,E2F2,E2F3:TFDP1,TFDP2: [nucleoplasm] (Bos taurus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Bos taurus)
PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Bos taurus)
as an output of
APC/C:Cdh1-mediated degradation of Skp2 (Bos taurus)
RB1 translocates to the nucleus (Bos taurus)
Other forms of this molecule
phospho-RB1 [nucleoplasm]
RB1 [cytosol]
phospho-RB1 [nucleoplasm]
phospho-RB1 [nucleoplasm]
phospho-RB1 [nucleoplasm]
phospho-RB1 [nucleoplasm]
phospho-RB1 [nucleoplasm]
phospho-RB1 [nucleoplasm]
phospho-RB1 [nucleoplasm]
phospho-RB1 [nucleoplasm]
phospho-RB1 [nucleoplasm]
phospho-RB1 [nucleoplasm]
phospho-RB1 [nucleoplasm]
phospho-RB1 [nucleoplasm]
phospho-RB1 [nucleoplasm]
phospho-RB1 [nucleoplasm]
Inferred From
RB1 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000139687
Ensembl
ENSBTAT00000008728
,
ENSBTAG00000006640
,
ENSBTAP00000008728
VGNC
33768
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