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What is Reactome ?
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POLD2 [nucleoplasm]
Stable Identifier
R-BTA-68443
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
POLD2, P49004
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
S Phase (Bos taurus)
Synthesis of DNA (Bos taurus)
DNA strand elongation (Bos taurus)
Lagging Strand Synthesis (Bos taurus)
Polymerase switching (Bos taurus)
Formation of Processive Complex (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive synthesis on the lagging strand (Bos taurus)
Formation of Okazaki fragments (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Formation of the Flap Intermediate (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Removal of the Flap Intermediate (Bos taurus)
RPA binds to the Flap (Bos taurus)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Recruitment of Dna2 endonuclease (Bos taurus)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Removal of RNA primer and dissociation of RPA and Dna2 (Bos taurus)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Removal of remaining Flap (Bos taurus)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Leading Strand Synthesis (Bos taurus)
Polymerase switching (Bos taurus)
Formation of Processive Complex (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Chromosome Maintenance (Bos taurus)
Telomere Maintenance (Bos taurus)
Extension of Telomeres (Bos taurus)
Telomere C-strand (Lagging Strand) Synthesis (Bos taurus)
Disassociation of Processive Complex and Completed Telomere End (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Polymerase switching on the C-strand of the telomere (Bos taurus)
Formation of Processive Complex on the C-strand of the telomere (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive synthesis on the C-strand of the telomere (Bos taurus)
Formation of C-strand Okazaki fragments (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Formation of the Flap Intermediate on the C-strand (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Joining of adjacent Okazaki fragments of the C-strand (Bos taurus)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Removal of the Flap Intermediate from the C-strand (Bos taurus)
RPA binds to the Flap on the C-strand (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Recruitment of DNA2 endonuclease to the C strand (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Removal of remaining Flap from the C-strand (Bos taurus)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
DNA Repair (Bos taurus)
Base Excision Repair (Bos taurus)
Resolution of Abasic Sites (AP sites) (Bos taurus)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Bos taurus)
PCNA-Dependent Long Patch Base Excision Repair (Bos taurus)
LIG1 binds APEX1 and PCNA at SSB (Bos taurus)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
LIG1 bound to APEX1 and PCNA ligates SSB (Bos taurus)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Bos taurus)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
POLD,POLE-mediated DNA strand displacement synthesis (Bos taurus)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
DNA Damage Bypass (Bos taurus)
Recognition of DNA damage by PCNA-containing replication complex (Bos taurus)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Bos taurus)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Bos taurus)
Termination of translesion DNA synthesis (Bos taurus)
POLD,POLE binds deISGylated PCNA after TLS (Bos taurus)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
DNA Double-Strand Break Repair (Bos taurus)
Homology Directed Repair (Bos taurus)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Bos taurus)
HDR through Homologous Recombination (HRR) (Bos taurus)
D-loop extension by DNA polymerases (Bos taurus)
PCNA:POLD,POLE,POLH,POLK:RPA:RFC [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Mismatch Repair (Bos taurus)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) (Bos taurus)
DNA polymerase delta polymerizes DNA across single stranded gap (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (Bos taurus)
DNA polymerase delta polymerizes DNA across single stranded gap (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Nucleotide Excision Repair (Bos taurus)
Global Genome Nucleotide Excision Repair (GG-NER) (Bos taurus)
Dual Incision in GG-NER (Bos taurus)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Bos taurus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
POLD,POLE,POLK [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Gap-filling DNA repair synthesis and ligation in GG-NER (Bos taurus)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Bos taurus)
Dual incision in TC-NER (Bos taurus)
3' incision by ERCC5 (XPG) in TC-NER (Bos taurus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Bos taurus)
POLD,POLE,POLK [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Gap-filling DNA repair synthesis and ligation in TC-NER (Bos taurus)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE [nucleoplasm] (Bos taurus)
POLD,POLE [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
DNA Replication (Bos taurus)
Synthesis of DNA (Bos taurus)
DNA strand elongation (Bos taurus)
Lagging Strand Synthesis (Bos taurus)
Polymerase switching (Bos taurus)
Formation of Processive Complex (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive synthesis on the lagging strand (Bos taurus)
Formation of Okazaki fragments (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Formation of the Flap Intermediate (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Removal of the Flap Intermediate (Bos taurus)
RPA binds to the Flap (Bos taurus)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Recruitment of Dna2 endonuclease (Bos taurus)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Removal of RNA primer and dissociation of RPA and Dna2 (Bos taurus)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Removal of remaining Flap (Bos taurus)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Leading Strand Synthesis (Bos taurus)
Polymerase switching (Bos taurus)
Formation of Processive Complex (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
Processive complex [nucleoplasm] (Bos taurus)
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
POLD2 [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:P49004
Gene Names
POLD2
Reference Genes
BioGPS Gene:281991 POLD2
ENSEMBL:ENSBTAG00000012241
ENSEMBL:ENSBTAG00000012241.5 POLD2
KEGG Gene (Bos taurus):281991 POLD2
Monarch:281991 POLD2
NCBI Gene:281991 POLD2
Reference Transcript
RefSeq:XM_015469965.1 POLD2
RefSeq:XM_015469966.1 POLD2
RefSeq:NM_174428.3 POLD2
Other Identifiers
281991
GO:0000228
GO:0003677
GO:0005634
GO:0005694
GO:0006259
GO:0006260
GO:0006271
GO:0006281
GO:0006974
GO:0043226
GO:0043625
GO:0071897
Participates
as a component of
DNA Polymerase delta tetramer [nucleoplasm] (Bos taurus)
Inferred From
POLD2 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_015325451.1
,
XP_015325452.1
,
NP_776853.2
OpenTargets
ENSG00000106628
Ensembl
ENSBTAG00000012241
,
ENSBTAT00000016237
,
ENSBTAP00000016237
VGNC
33114
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