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HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane]
Stable Identifier
R-BTA-6806977
Type
Complex
Species
Bos taurus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Bos taurus)
Intracellular signaling by second messengers (Bos taurus)
PIP3 activates AKT signaling (Bos taurus)
Negative regulation of the PI3K/AKT network (Bos taurus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activator:PI3K [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PI3K [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activator:PI3K [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PI3K [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
RAS GEFs promote RAS nucleotide exchange (Bos taurus)
RAS GEFs [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:SOS1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:RANBP9:SOS1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2:GRB2:SOS1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by MET (Bos taurus)
MET Receptor Activation (Bos taurus)
MET dimers autophosphorylate (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MET activates PI3K/AKT signaling (Bos taurus)
Activated MET binds GAB1 (Bos taurus)
HGF:p-4Y-MET dimer:GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
Activated MET binds GAB1 and GRB2 (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MET bound PI3K generates PIP3 (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PI3K [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MET phosphorylates GAB1 (Bos taurus)
HGF:p-4Y-MET dimer:GAB1,HGF:p-4Y-MET dimer:GRB2:GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
Phosphorylated GAB1 recruits PI3K to MET (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PI3K [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MET activates PTPN11 (Bos taurus)
GAB1 binds PTPN11 (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PTPN11 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MET activates RAS signaling (Bos taurus)
Activated MET binds RANBP9 and SOS1 (Bos taurus)
HGF:p-4Y-MET dimer:RANBP9:SOS1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
Activated MET recruits GRB2-1:SOS1 (Bos taurus)
HGF:p-4Y MET dimer:MUC20 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:SOS1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MET binds SHC1-2 (Bos taurus)
HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MET phosphorylates SHC1-2 (Bos taurus)
HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MUC20 binds MET and inhibits GRB2 binding (Bos taurus)
HGF:p-4Y MET dimer:MUC20 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:SOS1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Bos taurus)
HGF:p-4Y-MET dimer:RANBP9:SOS1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Bos taurus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2:GRB2:SOS1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
SHC1-2 bound to MET recruits GRB2:SOS1 (Bos taurus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2:GRB2:SOS1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MET activates STAT3 (Bos taurus)
MET phosphorylates STAT3 (Bos taurus)
HGF:p-4Y-MET dimer:STAT3 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
STAT3 binds activated MET receptor (Bos taurus)
HGF:p-4Y-MET dimer:STAT3 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MET promotes cell motility (Bos taurus)
MET activates PTK2 signaling (Bos taurus)
MET phosphorylates PTK2 (Bos taurus)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y397-PTK2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
PTK2 autophosphorylates (Bos taurus)
HGF:p-4Y-MET dimer:PTK2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y397-PTK2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
PTK2 binds activated MET (Bos taurus)
HGF:p-4Y-MET dimer:PTK2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
SRC phosphorylates PTK2 (Bos taurus)
HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
p-Y397-PTK2 binds SRC (Bos taurus)
HGF:p-4Y-MET dimer:p-Y397-PTK2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y397-PTK2 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MET activates RAP1 and RAC1 (Bos taurus)
CRK,CRKL recruits RAC1 GEF to activated MET (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:(DOCK7) [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
DOCK7 activates RAC1 (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:(DOCK7) [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
GAB1 recruits CRK,CRKL to MET (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
RAPGEF1 activates RAP1 (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
RAPGEF1 binds CRK,CRKL (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MET interacts with TNS proteins (Bos taurus)
MET binds TNS3 (Bos taurus)
HGF:p-4Y-MET dimer:TNS3 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MET binds TNS4 (Bos taurus)
HGF:p-4Y-MET dimer:TNS4:ITGB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MET receptor recycling (Bos taurus)
GGA3 associates with activated MET receptor (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Bos taurus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
Negative regulation of MET activity (Bos taurus)
CBL binds MET (Bos taurus)
HGF:p-4Y-MET dimer,(HGF:p-Y1003,4Y-METdimer) [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2:CBL,(HGF:p-Y1003,4Y-MET dimer:CBL) [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2:CBL [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1003,4Y-MET dimer:CBL [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
CBL monoubiquitinates activated MET (Bos taurus)
HGF:p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
MET phosphorylates CBL (Bos taurus)
HGF:p-4Y-MET dimer,(HGF:p-Y1003,4Y-METdimer) [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2:CBL,(HGF:p-Y1003,4Y-MET dimer:CBL) [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2:CBL [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-Y1003,4Y-MET dimer:CBL [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
PTPN1 and PTPN2 dephosphorylate MET (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
PTPRJ dephosphorylates MET (Bos taurus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
HGF dimer:p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(Bos taurus)
Participates
as an input of
MUC20 binds MET and inhibits GRB2 binding (Bos taurus)
PTPRJ dephosphorylates MET (Bos taurus)
PTPN1 and PTPN2 dephosphorylate MET (Bos taurus)
STAT3 binds activated MET receptor (Bos taurus)
MET binds TNS4 (Bos taurus)
MET binds TNS3 (Bos taurus)
PTK2 binds activated MET (Bos taurus)
Activated MET binds GAB1 and GRB2 (Bos taurus)
Activated MET binds GAB1 (Bos taurus)
MET binds SHC1-2 (Bos taurus)
Activated MET recruits GRB2-1:SOS1 (Bos taurus)
Activated MET binds RANBP9 and SOS1 (Bos taurus)
as an output of
RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Bos taurus)
MET phosphorylates STAT3 (Bos taurus)
MET dimers autophosphorylate (Bos taurus)
as a component of
HGF:p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2:CBL [plasma membrane] (Bos taurus)
HGF:p-Y1003,4Y-MET dimer:CBL [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:STAT3 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:TNS4:ITGB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:TNS3 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y397-PTK2 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:PTK2 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] (Bos taurus)
HGF:p-4Y MET dimer:MUC20 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:SOS1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:RANBP9:SOS1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Bos taurus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Bos taurus)
as a member of
HGF:p-4Y-MET dimer,(HGF:p-Y1003,4Y-METdimer) [plasma membrane] (Bos taurus)
Inferred From
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane]
(Homo sapiens)
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