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GTF2B [nucleoplasm]
Stable Identifier
R-BTA-65888
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
GTF2B, F2Z4J6
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
RNA Polymerase II Pre-transcription Events (Bos taurus)
Abortive Initiation Before Second Transition (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Pol II Promoter Escape Complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Abortive initiation after formation of the first phosphodiester bond (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
pol II transcription complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Fall Back to Closed Pre-initiation Complex (Bos taurus)
pol II closed pre-initiation complex [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
pol II open pre-initiation complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
RNA Polymerase II Transcription Initiation And Promoter Clearance (Bos taurus)
RNA Polymerase II Promoter Escape (Bos taurus)
Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Addition of the third nucleotide on the nascent transcript (Bos taurus)
pol II transcription complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Unwinding DNA for the nascent transcript (Bos taurus)
pol II transcription complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Unwinding of DNA for the Nascent Transcript: Second Transition (Bos taurus)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
RNA Polymerase II Promoter Opening: First Transition (Bos taurus)
pol II closed pre-initiation complex [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
pol II open pre-initiation complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
RNA Polymerase II Transcription Initiation (Bos taurus)
NTP Binds Active Site of RNA Polymerase II (Bos taurus)
Pol II initiation complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
pol II open pre-initiation complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Newly Formed Phosphodiester Bond Stabilized and PPi Released (Bos taurus)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
pol II transcription complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Bos taurus)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Pol II initiation complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Bos taurus)
Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Binding of TFIIE to the growing preinitiation complex (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Formation of the closed pre-initiation complex (Bos taurus)
pol II closed pre-initiation complex [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
RNA polymerase II transcribes snRNA genes (Bos taurus)
CBCAP complex binds 7-methylguanosine cap of snRNA (Bos taurus)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Bos taurus)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Bos taurus)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Integrator complex processes the 3' end of snRNA (Bos taurus)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Pre-snRNA is elongated and capped with 7-methylguanosine (Bos taurus)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
Pre-snRNA transcript initiation, Integrator binding, LEC binding (Bos taurus)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Bos taurus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Bos taurus)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Bos taurus)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Bos taurus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
GTF2B [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:F2Z4J6
Gene Names
GTF2B
Reference Genes
ENSEMBL:ENSBTAG00000000504.5
ENSEMBL:ENSBTAG00000000504.6 GTF2B
Other Identifiers
513231
GO:0000776
GO:0000793
GO:0000979
GO:0000993
GO:0001174
GO:0003677
GO:0003824
GO:0005634
GO:0005654
GO:0005669
GO:0005694
GO:0006351
GO:0006366
GO:0006367
GO:0007010
GO:0007059
GO:0008270
GO:0010467
GO:0016251
GO:0016407
GO:0016604
GO:0016740
GO:0017025
GO:0019083
GO:0022414
GO:0032153
GO:0032993
GO:0042585
GO:0043226
GO:0046966
GO:0051123
GO:0051177
GO:0051225
GO:0051276
GO:0065003
GO:0090575
GO:0140013
GO:0140223
GO:0140297
GO:1990114
GO:1990841
Participates
as an input of
General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Bos taurus)
Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Bos taurus)
as a component of
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Bos taurus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Bos taurus)
Pol II Promoter Escape Complex [nucleoplasm] (Bos taurus)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Bos taurus)
pol II open pre-initiation complex [nucleoplasm] (Bos taurus)
Pol II initiation complex [nucleoplasm] (Bos taurus)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Bos taurus)
pol II transcription complex [nucleoplasm] (Bos taurus)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Bos taurus)
as an output of
Abortive initiation after formation of the first phosphodiester bond (Bos taurus)
Abortive Initiation Before Second Transition (Bos taurus)
Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Bos taurus)
Inferred From
GTF2B [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000137947
Ensembl
ENSBTAT00000044137
,
ENSBTAG00000000504
,
ENSBTAP00000041650
VGNC
29693
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