Reactome | NDUFB7 [mitochondrial inner membrane]

NDUFB7 [mitochondrial inner membrane]

Stable Identifier

R-BTA-59940

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

mitochondrial inner membrane

Synonyms

NDUFB7, Q02368

Locations in the PathwayBrowser

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Metabolism (Bos taurus)

- Aerobic respiration and respiratory electron transport (Bos taurus)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Bos taurus)
    - Respiratory electron transport (Bos taurus)
      - Complex I biogenesis (Bos taurus)
        
        Intermediate 1 binds HP subcomplex to form Intermediate 2 (Bos taurus)
        
        HP subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        NDUFB7 [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        HP subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        NDUFB7 [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        HP subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        NDUFB7 [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        HP subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        NDUFB7 [mitochondrial inner membrane] (Bos taurus)
        
        ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Bos taurus)
        
        550kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        HP subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        NDUFB7 [mitochondrial inner membrane] (Bos taurus)
        
        815kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        550kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        HP subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        NDUFB7 [mitochondrial inner membrane] (Bos taurus)
        
        Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Bos taurus)
        
        815kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        550kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        HP subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        NDUFB7 [mitochondrial inner membrane] (Bos taurus)
        
        980kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        815kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        550kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        HP subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        NDUFB7 [mitochondrial inner membrane] (Bos taurus)
        
        The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        HP subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        NDUFB7 [mitochondrial inner membrane] (Bos taurus)
        
        550kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        HP subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        NDUFB7 [mitochondrial inner membrane] (Bos taurus)
        
        The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Bos taurus)
        
        980kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        815kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        550kDa complex [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 [mitochondrial inner membrane] (Bos taurus)
        
        HP subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        NDUFB7 [mitochondrial inner membrane] (Bos taurus)
        
        Complex I [mitochondrial inner membrane] (Bos taurus)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        HP subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        NDUFB7 [mitochondrial inner membrane] (Bos taurus)
      - Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Bos taurus)
        
        Complex I [mitochondrial inner membrane] (Bos taurus)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Bos taurus)
        
        HP subcomplex [mitochondrial inner membrane] (Bos taurus)
        
        NDUFB7 [mitochondrial inner membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:Q02368

Gene Names

NDUFB7

Reference Genes

BioGPS Gene:338065 NDUFB7

ENSEMBL:ENSBTAG00000012634

ENSEMBL:ENSBTAG00000012634.4 NDUFB7

KEGG Gene (Bos taurus):338065 NDUFB7

Monarch:338065 NDUFB7

NCBI Gene:338065 NDUFB7

Reference Transcript

RefSeq:NM_176660.2 NDUFB7

Other Identifiers

338065

GO:0003824

GO:0005215

GO:0005739

GO:0005743

GO:0005747

GO:0005758

GO:0006091

GO:0007005

GO:0008137

GO:0016020

GO:0016491

GO:0022900

GO:0032981

GO:0043226

GO:0065003

GO:0070469

Participates

as a component of

HP subcomplex [mitochondrial inner membrane] (Bos taurus)

Inferred From

NDUFB7 [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

NP_788833.1

OpenTargets

ENSG00000099795

Ensembl

ENSBTAG00000012634, ENSBTAT00000016768, ENSBTAP00000016768

VGNC

31966

PDB

5LDX, 5LDW, 7R4D, 5LC5, 7R4F, 7R43, 7QSD, 7R42, 7R41, 7DKF, 7R4C, 7R48, 7DGZ, 7R46, 7R47, 7QSO, 7QSK, 7DH0, 7DGR, 5O31, 7R4G, 7DGQ, 7R45, 7R44, 7QSN, 7QSM, 7QSL, 7DGS

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