Reactome | MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane]

MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-BTA-5689836

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

MCFD2, A0A3Q1MFL2

Locations in the PathwayBrowser

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Metabolism of proteins (Bos taurus)

- Post-translational protein modification (Bos taurus)
  - Asparagine N-linked glycosylation (Bos taurus)
    - Transport to the Golgi and subsequent modification (Bos taurus)
      - ER to Golgi Anterograde Transport (Bos taurus)
        
        COPII-mediated vesicle transport (Bos taurus)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        hexameric LMAN1:MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)

Vesicle-mediated transport (Bos taurus)

- Membrane Trafficking (Bos taurus)
  - ER to Golgi Anterograde Transport (Bos taurus)
    - COPII-mediated vesicle transport (Bos taurus)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Bos taurus)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        hexameric LMAN1:MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:A0A3Q1MFL2

Gene Names

MCFD2

Reference Genes

ENSEMBL:ENSBTAG00000003358.6

Other Identifiers

616647

GO:0005509

GO:0046872

Participates

as a component of

hexameric LMAN1:MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)

Other forms of this molecule

MCFD2 [endoplasmic reticulum membrane]

MCFD2 [ER to Golgi transport vesicle membrane]

Inferred From

MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000180398

Ensembl

ENSBTAG00000003358, ENSBTAP00000067747, ENSBTAT00000077670

VGNC

31304

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